HDAC4 and SUMO2

  • Number of citations of the paper that reports this interaction (PubMedID 11451954)
  • 256
  • Data Source:
  • HPRD (in vitro, in vivo)

HDAC4

SUMO2

Description histone deacetylase 4 small ubiquitin like modifier 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
  • Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals ( 22959728)
  • Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
  • Blond vs. brown/black hair color ( 30531825)
  • Chronotype ( 30696823)
  • Diastolic blood pressure ( 30224653 30487518)
  • Estimated glomerular filtration rate after 5 years in renal transplantation (recipient effect) ( 30920136)
  • Heel bone mineral density ( 30598549)
  • Intra-individual response time variability (selective attention) ( 30287865)
  • Male-pattern baldness ( 22693459)
  • Mean arterial pressure ( 29403010 30487518)
  • Nevus count ( 30429480)
  • Nevus count or cutaneous melanoma ( 30429480)
  • Obstructive sleep apnea trait (apnea hypopnea index) ( 29077507)
  • Perioperative myocardial infarction in coronary artery bypass surgery ( 25948407)
  • Pulmonary function ( 21946350)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Systolic blood pressure ( 30487518)
  • Gamma glutamyl transferase levels ( 29403010)
Interacting Genes 88 interacting genes: ACTA1 ANKRA2 ANKRD11 APP AR ATF3 ATRX BCL6 BCOR BRMS1 CACNA1C CAMK4 CBX5 CCDC136 CDKN1A CDR2 CEBPD CIITA CSRP3 CTBP1 EFEMP2 ESR1 GATA1 GCM1 GNB1 GOLGA2 GSK3B HDAC3 HDAC7 HDAC9 HNF4A IFRD1 IKZF2 JDP2 KRT31 KRT38 KRT40 LCOR LDOC1 LZTR1 MAP1S MAPK1 MAPK3 MECOM MEF2A MEF2B MEF2C MEF2D MEGF10 MIF4GD MTUS2 NACC1 NCOR2 NFKB2 NFKBIE NPPB NR1H2 NR2C1 NR2C2 NUP155 PNMA1 PPARD PPARG PTPA RANBP2 RARA RBBP4 REV3L RFXANK RINT1 RUNX2 RUNX3 RUVBL2 RXRA SMAD3 SRF SS18L1 SUMO1 SUMO2 SYK TNFRSF14 UBE2I YWHAE YWHAG YWHAQ YWHAZ ZBTB16 ZNF354A 179 interacting genes: ABRAXAS1 AHNAK ALAS1 ANAPC2 ANXA1 ATF7IP ATRX ATXN7 BABAM2 BAD BAZ1A BAZ1B BLM BRCC3 C18orf25 CAD CARS1 CCNE2 CENPC CHAF1A CHAF1B CHAMP1 CHD3 CHD4 CMTM6 CSNK2B CTNND1 CUL3 CUX1 DAXX DCD DDX17 DDX21 DDX3X DNM1L EEF1A1 EEF1G EGLN3 EME1 ENO1 EP300 ERCC4 EXOSC10 EXOSC9 FOS GATAD2B HDAC1 HDAC2 HDAC4 HDAC9 HIPK2 HNRNPF HNRNPH1 HNRNPK HOMEZ HP1BP3 HSF2 HSP90AB1 HSPA1A HSPA8 HSPA9 IPO5 JUN KALRN KDM1A KIF18B LAS1L LEF1 MAF1 MAST2 MDC1 MDN1 MKI67 MRE11 MSH2 MSX1 MTA1 MTA2 MUS81 MYB NBN NFE2L2 NOL9 NOP2 NUMA1 PARN PELP1 PFKM PHF5A PHF8 PIAS1 PIAS2 PIAS3 PIAS4 PML POGZ PRKDC RAD50 RAD51 RAD54L2 RANBP2 RANGAP1 RBBP4 RBBP7 RCOR1 RCOR2 RCOR3 RNF111 RNF168 RNF216 RNF4 RNF8 RPL3 RPL4 RUVBL1 SAE1 SENP1 SENP2 SENP3 SENP5 SENP6 SENP7 SETDB1 SETX SIMC1 SLC22A2 SLX4IP SMCHD1 SOBP SOX10 SOX6 SP100 SSRP1 SUPT16H TDG TDP2 TEAD3 TEX10 TMPO TNIP1 TOP2A TOP2B TOPORS TP53BP1 TP53BP2 TPR TRAF1 TRIM26 TRIM28 TRIM63 TRIML2 TUBA1B TUBB TUBB4B TUBB6 UBA2 UBE2I USP11 USP25 USP28 USP7 USPL1 VIM WRN XRCC5 XRCC6 ZBED1 ZBTB2 ZBTB25 ZBTB33 ZCCHC12 ZCCHC7 ZHX1 ZMAT3 ZMYM3 ZMYM4 ZMYM5 ZNF451 ZNF496
Entrez ID 9759 6613
HPRD ID 05610 04332
Ensembl ID ENSG00000068024 ENSG00000188612
Uniprot IDs P56524 A0A024R8S3 P61956
PDB IDs 2H8N 2O94 2VQJ 2VQM 2VQO 2VQQ 2VQV 2VQW 3UXG 3UZD 3V31 4CBT 4CBY 5A2S 5ZOO 5ZOP 6FYZ 1WM2 1WM3 1WZ0 1Z5Q 2AWT 2CKH 2D07 2IO0 2IO3 2IYD 2N1W 2N9E 2RPQ 3UIN 3UIO 3ZO5 4BKG 4NPN 5D2M 5ELU 5EQL 5GHB 5GHC
Enriched GO Terms of Interacting Partners?
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