VGLL4 and LRRK1

Number of citations of the paper that reports this interaction (PubMedID 29513927)
4

Data Source:
BioGRID (pull down)

		VGLL4	LRRK1
Description		vestigial like family member 4	leucine rich repeat kinase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Mitochondrion Cytosol
	Molecular Function	Transcription Coactivator Binding Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding GTP Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription, DNA-templated	Protein Phosphorylation Osteoclast Development Bone Resorption Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa ( 21079607) Blond vs. brown/black hair color ( 30531825) Body mass index ( 28892062) Chronic obstructive pulmonary disease ( 30804561) Clopidogrel active metabolite levels ( 28207573) Height ( 25429064 31562340) Male-pattern baldness ( 28196072) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Moderate-to-late spontaneous preterm birth ( 31194736) Offspring birth weight ( 31043758) Optic disc area ( 28073927) Relative hand skill in reading disability ( 24068947) Spontaneous preterm birth with premature rupture of membranes ( 31194736)	Central corneal thickness ( 28171582 31798171 29760442) Corneal structure ( 23291589) Height ( 28552196)
Interacting Genes		9 interacting genes: CDK6 DAPK1 LRRK1 LRRK2 MEF2A MEF2C MFHAS1 TEAD1 TERF2IP	53 interacting genes: ABL1 BAG1 BAG2 BAG3 BAG5 BLOC1S5 C11orf52 CBLB CCL21 CD2BP2 CDC42EP3 CHGB CKAP2 CLVS1 CPLX3 CWC15 ECHS1 EGFR ENKUR EPHA8 FAM184A FBXL14 FGFR2 FLT4 FOXP1 GAK GNAZ GPBP1L1 ITCH KIF20A MATK MTG1 NEK1 NUDT16L1 ODF2 PAK6 PDCD4 PLK1 POLR2M RAB29 RET SCEL SELENOS SH2D2A SNX21 SNX9 STUB1 TCF25 TEC TEX33 TIRAP TM2D3 VGLL4
Entrez ID		9686	79705
HPRD ID		11672	14319
Ensembl ID		ENSG00000144560	ENSG00000154237
Uniprot IDs		A0A075B6E4 A0A0A6YYI5 G5E9M7 G5E9M9 Q14135	Q38SD2
PDB IDs
Enriched GO Terms of Interacting Partners?
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