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LRRK1

Description leucine rich repeat kinase 1
Image No pdb structure
GO Annotations Cellular Component
  • Mitochondrion
  • Cytosol
Molecular Function
  • Protein Serine/threonine Kinase Activity
  • Protein Binding
  • ATP Binding
  • GTP Binding
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Protein Phosphorylation
  • Osteoclast Development
  • Bone Resorption
  • Positive Regulation Of Peptidyl-tyrosine Phosphorylation
  • Negative Regulation Of Peptidyl-tyrosine Phosphorylation
  • Positive Regulation Of Canonical Wnt Signaling Pathway
  • Positive Regulation Of Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS
  • Central corneal thickness ( 28171582 31798171 29760442)
  • Corneal structure ( 23291589)
  • Height ( 28552196)
Interacting Genes 53 interacting genes: ABL1 BAG1 BAG2 BAG3 BAG5 BLOC1S5 C11orf52 CBLB CCL21 CD2BP2 CDC42EP3 CHGB CKAP2 CLVS1 CPLX3 CWC15 ECHS1 EGFR ENKUR EPHA8 FAM184A FBXL14 FGFR2 FLT4 FOXP1 GAK GNAZ GPBP1L1 ITCH KIF20A MATK MTG1 NEK1 NUDT16L1 ODF2 PAK6 PDCD4 PLK1 POLR2M RAB29 RET SCEL SELENOS SH2D2A SNX21 SNX9 STUB1 TCF25 TEC TEX33 TIRAP TM2D3 VGLL4
Entrez ID 79705
HPRD ID 14319
Ensembl ID ENSG00000154237
Uniprot IDs Q38SD2
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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