ARHGAP12 and TRIP10

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ARHGAP12	TRIP10
Description		Rho GTPase activating protein 12	thyroid hormone receptor interactor 10
Image		No pdb structure
GO Annotations	Cellular Component	Phagocytic Cup Cytoplasm Cytosol	Phagocytic Cup Nucleoplasm Cytoplasm Lysosome Golgi Apparatus Cytosol Cytoskeleton Cell Cortex Cell Projection Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	GTPase Activator Activity	Protein Binding Lipid Binding Identical Protein Binding
	Biological Process	Morphogenesis Of An Epithelial Sheet Phagocytosis, Engulfment Actin Filament Organization Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Negative Regulation Of Small GTPase Mediated Signal Transduction	Endocytosis Cell Communication Signal Transduction Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Membrane Organization
Pathways		Rho GTPase cycle	Rho GTPase cycle Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		C-reactive protein levels ( 24763700) Glycine levels ( 30837465) Intraocular pressure ( 31959993) Pulse pressure ( 28135244 27841878) Systolic blood pressure ( 27841878) Uterine fibroids ( 31649266)
Interacting Genes		3 interacting genes: SRPK1 SRPK2 TRIP10	28 interacting genes: ABL2 AKAP9 ARHGAP12 ARHGAP17 CDC42 CREBBP CTNNB1 DNM2 HTT LYN PDE6G POT1 PRKACA RHOJ RHOQ RXRA SH3BP1 SMARCE1 SMURF1 SRC STAT3 TERF1 THRB TINF2 WAS WASF1 WASL WBP11
Entrez ID		94134	9322
HPRD ID		06446	05142
Ensembl ID		ENSG00000165322	ENSG00000125733
Uniprot IDs		Q1RLN5 Q8IWW6	Q15642 W4VSQ9
PDB IDs			2CT4 2EFK 2KE4
Enriched GO Terms of Interacting Partners?
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