SYTL5 and RAB27B

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		SYTL5	RAB27B
Description		synaptotagmin like 5	RAB27B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Exocytic Vesicle	Cell Late Endosome Golgi Apparatus Golgi Stack Plasma Membrane Endomembrane System Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm
	Molecular Function	Protein Binding Phospholipid Binding Rab GTPase Binding Neurexin Family Protein Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis	Platelet Degranulation Intracellular Protein Transport Melanosome Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport
Pathways			Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Anorexia nervosa ( 23568457) Erectile dysfunction and prostate cancer treatment ( 20932654)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		6 interacting genes: CEP70 RAB27A RAB27B RAB3A RAB6A WAC	8 interacting genes: DHPS MLPH RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D
Entrez ID		94122	5874
HPRD ID		06736	04846
Ensembl ID		ENSG00000147041	ENSG00000041353
Uniprot IDs		Q8TDW5	O00194
PDB IDs			2F7S
Enriched GO Terms of Interacting Partners?
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