RAB27B and DHPS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RAB27B	DHPS
Description		RAB27B, member RAS oncogene family	deoxyhypusine synthase
Image
GO Annotations	Cellular Component	Cell Late Endosome Golgi Apparatus Golgi Stack Plasma Membrane Endomembrane System Apical Plasma Membrane Trans-Golgi Network Transport Vesicle Secretory Granule Platelet Dense Granule Membrane Multivesicular Body Membrane Melanosome Zymogen Granule Membrane Extracellular Exosome Anchored Component Of Synaptic Vesicle Membrane Axon Cytoplasm	Cytoplasm Cytosol
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Domain Specific Binding Myosin V Binding	Protein Binding Deoxyhypusine Synthase Activity Identical Protein Binding
	Biological Process	Platelet Degranulation Intracellular Protein Transport Melanosome Transport Rab Protein Signal Transduction Positive Regulation Of Exocytosis Synaptic Vesicle Endocytosis Multivesicular Body Sorting Pathway Anterograde Axonal Protein Transport	Translation Spermidine Metabolic Process Positive Regulation Of Cell Proliferation Peptidyl-lysine Modification To Peptidyl-hypusine
Pathways		Platelet degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Hypusine synthesis from eIF5A-lysine
Drugs			1-Guanidinium-7-Aminoheptane
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Body mass index ( 28892062) Childhood body mass index ( 26604143) Depression ( 29700475) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		8 interacting genes: DHPS MLPH RPH3AL SYTL1 SYTL2 SYTL4 SYTL5 UNC13D	13 interacting genes: BRCA1 EIF5A EIF5A2 NIF3L1 NTAQ1 NUDT18 PTPRH RAB27B REL RPL9 UPF1 VASH1 ZNF138
Entrez ID		5874	1725
HPRD ID		04846	02969
Ensembl ID		ENSG00000041353	ENSG00000095059
Uniprot IDs		O00194	A0A024R7D0 A0A024R7E9 P49366
PDB IDs		2F7S	1DHS 1RLZ 1ROZ 1RQD
Enriched GO Terms of Interacting Partners?
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