CYTH2 and IPCEF1

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo, in vitro)

		CYTH2	IPCEF1
Description		cytohesin 2	interaction protein for cytohesin exchange factors 1
Image
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Growth Cone	Cytosol Plasma Membrane
	Molecular Function	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding	Peroxidase Activity Oxygen Carrier Activity Protein Binding Protein Domain Specific Binding
	Biological Process	Endocytosis Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction	Response To Oxidative Stress Oxygen Transport Cellular Oxidant Detoxification
Pathways		Intra-Golgi traffic
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Formic Acid 1D-myo-inositol 1,4,5-trisphosphate S,S-(2-Hydroxyethyl)Thiocysteine Brefeldin A
Diseases
GWAS		Abstraction and mental flexibility ( 31596458)	Allergic disease (asthma, hay fever or eczema) ( 29679657) Arterial stiffness index ( 31235810) Asthma (childhood onset) ( 27611488) Chronic lymphocytic leukemia ( 28165464 24292274)
Interacting Genes		31 interacting genes: ADORA2A ALDOA APC ARF1 ARF6 ARFGAP1 ARL4A ARL4D ARRB1 ARRB2 ATP6V0A1 ATP6V0A2 ATP6V0A4 CCDC120 CUX1 CYTIP DOCK1 GGA3 GNAQ INAVA IPCEF1 ITGB2 MAPK6 NUP62 PIK3CA PNPLA2 PRKCA PRKCB PRKCG TCIRG1 TRIM23	2 interacting genes: CYTH2 CYTH4
Entrez ID		9266	26034
HPRD ID		03925	17851
Ensembl ID		ENSG00000105443	ENSG00000074706
Uniprot IDs		Q99418	Q8WWN9
PDB IDs		1PBV 1R8M 1R8Q 1R8S 1S9D 4JMI 4JMO 4JWL 4JXH 4L5M 4Z21	5MR1
Enriched GO Terms of Interacting Partners?
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