IPCEF1 and CYTH2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo, in vitro)

		IPCEF1	CYTH2
Description		interaction protein for cytohesin exchange factors 1	cytohesin 2
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Golgi Membrane Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Growth Cone
	Molecular Function	Peroxidase Activity Oxygen Carrier Activity Protein Binding Protein Domain Specific Binding	ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Response To Oxidative Stress Oxygen Transport Cellular Oxidant Detoxification	Endocytosis Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction
Pathways			Intra-Golgi traffic
Drugs			Inositol 1,3,4,5-Tetrakisphosphate Formic Acid 1D-myo-inositol 1,4,5-trisphosphate S,S-(2-Hydroxyethyl)Thiocysteine Brefeldin A
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29679657) Arterial stiffness index ( 31235810) Asthma (childhood onset) ( 27611488) Chronic lymphocytic leukemia ( 28165464 24292274)	Abstraction and mental flexibility ( 31596458)
Interacting Genes		2 interacting genes: CYTH2 CYTH4	31 interacting genes: ADORA2A ALDOA APC ARF1 ARF6 ARFGAP1 ARL4A ARL4D ARRB1 ARRB2 ATP6V0A1 ATP6V0A2 ATP6V0A4 CCDC120 CUX1 CYTIP DOCK1 GGA3 GNAQ INAVA IPCEF1 ITGB2 MAPK6 NUP62 PIK3CA PNPLA2 PRKCA PRKCB PRKCG TCIRG1 TRIM23
Entrez ID		26034	9266
HPRD ID		17851	03925
Ensembl ID		ENSG00000074706	ENSG00000105443
Uniprot IDs		Q8WWN9	Q99418
PDB IDs		5MR1	1PBV 1R8M 1R8Q 1R8S 1S9D 4JMI 4JMO 4JWL 4JXH 4L5M 4Z21
Enriched GO Terms of Interacting Partners?
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