VAPA and RMDN3

Number of citations of the paper that reports this interaction (PubMedID 26496610)
285

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid)

		VAPA	RMDN3
Description		VAMP associated protein A	regulator of microtubule dynamics 3
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Bicellular Tight Junction Microtubule Cytoskeleton Integral Component Of Membrane Nuclear Membrane Vesicle Azurophil Granule Membrane Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site	Spindle Pole Cell Nucleus Mitochondrion Mitochondrial Outer Membrane Microtubule Integral Component Of Membrane Intercellular Bridge
	Molecular Function	Protein Binding Microtubule Binding Protein Domain Specific Binding FFAT Motif Binding Cadherin Binding Protein Heterodimerization Activity	Protein Binding
	Biological Process	ER To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Cell Death Viral Process Sphingolipid Biosynthetic Process Neuron Projection Development Protein Folding In Endoplasmic Reticulum Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neutrophil Degranulation Positive Regulation By Host Of Viral Release From Host Cell Negative Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Genome Replication Membrane Fusion Protein Localization To Endoplasmic Reticulum COPII-coated Vesicle Budding	Cellular Calcium Ion Homeostasis Apoptotic Process Cell Differentiation
Pathways		Sphingolipid de novo biosynthesis Neutrophil degranulation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Diverticular disease ( 30177863) FEV1 ( 30804560) Heel bone mineral density ( 30598549) Lung function (FEV1/FVC) ( 30804560) Metabolite levels ( 23823483) Peak expiratory flow ( 30804560) Pulmonary function (smoking interaction) ( 23284291)	Anxiety and stress-related disorders ( 31116379)
Interacting Genes		15 interacting genes: ADGRG7 ADRB2 APOD APP CACNG1 EGFR KCNB1 NSF OPRM1 OSBP RMDN3 SIK1 VAMP1 VAMP2 ZBTB22	6 interacting genes: EGFL8 PSEN1 VAPA YWHAB YWHAG YWHAZ
Entrez ID		9218	55177
HPRD ID		09299	07687
Ensembl ID		ENSG00000101558	ENSG00000137824
Uniprot IDs		Q9P0L0	A0A024R9P6 Q96TC7
PDB IDs		2RR3
Enriched GO Terms of Interacting Partners?
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