ZBED1 and ATRX

Number of citations of the paper that reports this interaction (PubMedID 22021382)
10

Data Source:
BioGRID (affinity chromatography technology, pull down)

		ZBED1	ATRX
Description		zinc finger BED-type containing 1	ATRX chromatin remodeler
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Centrosome Nuclear Membrane	Condensed Nuclear Chromosome, Centromeric Region Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Nuclear Body PML Body Nuclear Pericentric Heterochromatin Telomeric Heterochromatin Nuclear Subtelomeric Heterochromatin
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity	DNA Binding DNA Helicase Activity Chromatin Binding Protein Binding ATP Binding DNA Translocase Activity Methylated Histone Binding Histone Binding Metal Ion Binding Chromo Shadow Domain Binding
	Biological Process	Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II	Meiotic Spindle Organization DNA Repair DNA Methylation Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Chromatin Remodeling Regulation Of Transcription, DNA-templated Spermatogenesis Positive Regulation Of Nuclear Cell Cycle DNA Replication DNA Damage Response, Signal Transduction By P53 Class Mediator Forebrain Development Replication Fork Processing Positive Regulation Of Telomere Maintenance DNA Duplex Unwinding Post-embryonic Forelimb Morphogenesis Multicellular Organism Growth Positive Regulation Of Transcription By RNA Polymerase II Sertoli Cell Development Chromosome Organization Involved In Meiotic Cell Cycle Protein Localization To Chromosome, Telomeric Region Seminiferous Tubule Development Cellular Response To Hydroxyurea Regulation Of Histone H3-K9 Trimethylation Negative Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter Positive Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Telomeric
Pathways		SUMOylation of chromatin organization proteins
Drugs
Diseases			Syndromic X-linked mental retardation with epilepsy or seizures, including: West syndrome (WS); Partington syndrome (PRTS); Proud syndrome (ACCAG); XMR and epilepsy (XMRE); MRXHF1; XMR OPHN1-related (MRXSO) ; XELBD; XMR, Christianson type (MRXSC); Creatine deficiency syndrome (XL-CDS); Renpenning syndrome (RENS1); Epilepsy and mental retardation limited to females (EFMR); Periventricular nodular heterotopia (PVNH); Hydrocephalus (XLH); XMR, JARID1C related (MRXSJ); Boerjeson-Forssman syndrome (BFLS); CK syndrome (CKS) Thalassemia; Alpha thalassemia; Beta thalassemia; Alpha thalassemia, X-linked (ATRX) Non-syndromic X-linked mental retardation 46,XY disorders of sex development (Disorders of gonadal development), including: Gonadal agenesis; Complete and partial gonadal dysgenesis; Testis regression; Ovotesticular DSD
GWAS
Interacting Genes		29 interacting genes: AMOTL2 ATRX C1orf109 DGCR6 EFHC1 FABP4 FANCG GPN1 GPSM1 KDM1A KLHL40 LRRC20 MLH1 NIF3L1 NIP7 NUDT18 PIAS2 PRKAA1 PRKAR1A PSAP RENBP SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2B TTR UBE2I UCHL5	27 interacting genes: ATN1 AURKA BLM CALM1 CCSER2 CEP126 CREBBP DAXX EZH2 H3-3A H3C14 HDAC1 HDAC4 LUC7L2 MDM2 NEK1 NSD1 PTN PTPN4 RAD51 RASSF1 SUMO2 SVIL TP53 WRN ZBED1 ZNF512B
Entrez ID		9189	546
HPRD ID		02170	02069
Ensembl ID		ENSG00000214717	ENSG00000085224
Uniprot IDs		A0A024RBU4 O96006	A4LAA3 B4DLW1 P46100
PDB IDs		2CT5	2JM1 2LBM 2LD1 3QL9 3QLA 3QLC 3QLN 4W5A 5GRQ 5Y18 5Y6O 6G0O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?