ZBED1 and EFHC1

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		ZBED1	EFHC1
Description		zinc finger BED-type containing 1	EF-hand domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleoplasm Centrosome Nuclear Membrane	Spindle Pole Centrosome Axoneme Neuronal Cell Body Mitotic Spindle
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding SUMO Transferase Activity Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Protein Dimerization Activity	Calcium Ion Binding Protein Binding Protein C-terminus Binding Alpha-tubulin Binding
	Biological Process	Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Regulation Of Cell Division Cilium-dependent Cell Motility
Pathways		SUMOylation of chromatin organization proteins
Drugs
Diseases			Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS			Atopic march ( 26542096) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		29 interacting genes: AMOTL2 ATRX C1orf109 DGCR6 EFHC1 FABP4 FANCG GPN1 GPSM1 KDM1A KLHL40 LRRC20 MLH1 NIF3L1 NIP7 NUDT18 PIAS2 PRKAA1 PRKAR1A PSAP RENBP SORBS3 SPEF1 SSX2 SUMO2 TRAPPC2B TTR UBE2I UCHL5	18 interacting genes: CACNA1E DOK7 EFHC2 EIF4ENIF1 GOLGA2 HOMER3 IHO1 IKZF3 KCTD4 KRT15 REL RIMBP3 SH3GLB2 TCF4 TEX11 TRAF2 TRIP6 ZBED1
Entrez ID		9189	114327
HPRD ID		02170	10583
Ensembl ID		ENSG00000214717	ENSG00000096093
Uniprot IDs		A0A024RBU4 O96006	B2CKC5 Q5JVL4
PDB IDs		2CT5
Enriched GO Terms of Interacting Partners?
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