USP14 and FANCC

Number of citations of the paper that reports this interaction (PubMedID 14499622)
12

Data Source:
BioGRID (two hybrid)

		USP14	FANCC
Description		ubiquitin specific peptidase 14	FA complementation group C
Image			No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Cytosol Plasma Membrane Cell Surface Cytoplasmic Vesicle Synapse Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol Fanconi Anaemia Nuclear Complex
	Molecular Function	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Endopeptidase Inhibitor Activity Protein Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Proteasome Binding	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Chemical Synaptic Transmission Negative Regulation Of Endopeptidase Activity Protein Deubiquitination Innate Immune Response Regulation Of Chemotaxis Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process	Myeloid Cell Homeostasis DNA Repair Nucleotide-excision Repair Germ Cell Development Removal Of Superoxide Radicals Cellular Response To Oxidative Stress Interstrand Cross-link Repair Brain Morphogenesis Protein-containing Complex Assembly Neuronal Stem Cell Population Maintenance
Pathways		Ub-specific processing proteases	Fanconi Anemia Pathway TP53 Regulates Transcription of DNA Repair Genes
Drugs		Phenethyl Isothiocyanate
Diseases			Fanconi anemia
GWAS			Birth weight ( 31043758) Offspring birth weight ( 31043758) Polycystic ovary syndrome ( 26284813)
Interacting Genes		10 interacting genes: CCNB1 COPS5 CXCR4 FANCC SEM1 TRIM11 UBC USP15 USP21 USP28	34 interacting genes: AZIN1 CAPN10 CCNA2 CDK1 CTBP1 DNAJB1 FANCA FANCD2 FANCE FANCF FANCG GSTP1 HSP90AA1 HSP90B1 HSPA1A HSPA4 HSPA8 IK KRT1 MEOX2 MT-ATP6 POR PRDX3 PRPF31 RPL18 RPS3A SPTA1 SPTAN1 STAT1 STMN1 STMN2 TCERG1 USP14 ZBTB32
Entrez ID		9097	2176
HPRD ID		06279	01967
Ensembl ID		ENSG00000101557	ENSG00000158169
Uniprot IDs		P54578	A0A024R9N2 A0A087WW44 B4E3W2 Q00597
PDB IDs		2AYN 2AYO 5GJQ 6IIK 6IIL 6IIM 6IIN
Enriched GO Terms of Interacting Partners?
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