DNAJA3 and NOC4L

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DNAJA3	NOC4L
Description		DnaJ heat shock protein family (Hsp40) member A3	nucleolar complex associated 4 homolog
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Actin Filament Extrinsic Component Of Plasma Membrane Cell Junction Neuromuscular Junction Intracellular Membrane-bounded Organelle Postsynaptic Membrane	Nucleoplasm Nucleolus Integral Component Of Membrane Noc4p-Nop14p Complex Nuclear Membrane Small-subunit Processome
	Molecular Function	Protein Binding ATP Binding Hsp70 Protein Binding GTPase Regulator Activity Metal Ion Binding Unfolded Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitochondrial DNA Replication Protein Folding Activation-induced Cell Death Of T Cells Mitochondrion Organization Small GTPase Mediated Signal Transduction Cell Aging Negative Regulation Of Cell Proliferation Response To Heat T Cell Differentiation In Thymus Positive Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Skeletal Muscle Acetylcholine-gated Channel Clustering	Regulation Of Transcription By RNA Polymerase II RRNA Processing
Pathways			rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798) Schizophrenia ( 28991256) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Body mass index ( 26426971) Hirschsprung disease ( 26887379) Response to antidepressants (symptom improvement) ( 29160301) Response to SSRI (symptom remission) ( 29160301)
Interacting Genes		40 interacting genes: ATXN1 BRCA1 C2CD6 CARM1 COIL FAM131C FAM214B FBXO7 FOSL2 FRMD6 GCC1 GFI1B GRB2 HSPA1A HSPA8 IFNGR2 INPP5J JAK2 KDM1A KRAS MCPH1 MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 RAD51 RASA1 RELA RNF34 SMAD9 SMARCB1 STK16 TCF19 USP7 VHL ZBTB22	14 interacting genes: BHLHE40 DAZAP2 DNAJA3 IKZF1 KRT15 LINC00839 NECAB2 NT5C2 PLSCR1 PRSS23 TSC22D4 USHBP1 VIM ZNRD2
Entrez ID		9093	79050
HPRD ID		09758	14543
Ensembl ID		ENSG00000103423	ENSG00000184967
Uniprot IDs		B3KM81 Q53G26 Q59E88 Q96EY1	Q9BVI4
PDB IDs		2CTT 2DN9
Enriched GO Terms of Interacting Partners?
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