DNAJA3 and INPP5J

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		DNAJA3	INPP5J
Description		DnaJ heat shock protein family (Hsp40) member A3	inositol polyphosphate-5-phosphatase J
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cytosol Actin Filament Extrinsic Component Of Plasma Membrane Cell Junction Neuromuscular Junction Intracellular Membrane-bounded Organelle Postsynaptic Membrane	Ruffle Cytoplasm Cytosol Plasma Membrane Extrinsic Component Of Membrane Growth Cone Dendritic Shaft
	Molecular Function	Protein Binding ATP Binding Hsp70 Protein Binding GTPase Regulator Activity Metal Ion Binding Unfolded Protein Binding	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Inositol-polyphosphate 5-phosphatase Activity Protein Binding SH3 Domain Binding Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Inositol-1,4,5-trisphosphate 5-phosphatase Activity Inositol-1,3,4,5-tetrakisphosphate 5-phosphatase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Mitochondrial DNA Replication Protein Folding Activation-induced Cell Death Of T Cells Mitochondrion Organization Small GTPase Mediated Signal Transduction Cell Aging Negative Regulation Of Cell Proliferation Response To Heat T Cell Differentiation In Thymus Positive Regulation Of T Cell Proliferation Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Catalytic Activity Skeletal Muscle Acetylcholine-gated Channel Clustering	Phosphatidylinositol Biosynthetic Process Negative Regulation Of Neuron Projection Development Negative Regulation Of Microtubule Polymerization Negative Regulation Of Peptidyl-serine Phosphorylation Inositol Phosphate Metabolic Process Inositol Phosphate Dephosphorylation Phosphatidylinositol Dephosphorylation
Pathways			Synthesis of PIPs at the plasma membrane Synthesis of IP2, IP, and Ins in the cytosol Synthesis of IP3 and IP4 in the cytosol
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798) Schizophrenia ( 28991256) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		40 interacting genes: ATXN1 BRCA1 C2CD6 CARM1 COIL FAM131C FAM214B FBXO7 FOSL2 FRMD6 GCC1 GFI1B GRB2 HSPA1A HSPA8 IFNGR2 INPP5J JAK2 KDM1A KRAS MCPH1 MET MYO15B NFKBIA NFKBIB NOC4L NTRK1 OSGIN1 PRMT6 RAD51 RASA1 RELA RNF34 SMAD9 SMARCB1 STK16 TCF19 USP7 VHL ZBTB22	6 interacting genes: CDC23 DNAJA3 EPS8 GOLGA2 TRIM27 TRIM54
Entrez ID		9093	27124
HPRD ID		09758	07573
Ensembl ID		ENSG00000103423	ENSG00000185133
Uniprot IDs		B3KM81 Q53G26 Q59E88 Q96EY1	A0A087WVS7 B4DF95 Q15735
PDB IDs		2CTT 2DN9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?