EIF2B4 and EIF2B2

Number of citations of the paper that reports this interaction (PubMedID 28514442)
199

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vitro, in vivo)

		EIF2B4	EIF2B2
Description		eukaryotic translation initiation factor 2B subunit delta	eukaryotic translation initiation factor 2B subunit beta
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex	Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 2B Complex
	Molecular Function	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding Translation Initiation Factor Binding	Translation Initiation Factor Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding GTP Binding
	Biological Process	Ovarian Follicle Development Translational Initiation Regulation Of Translation Response To Heat Response To Glucose Oligodendrocyte Development Myelination Response To Peptide Hormone T Cell Receptor Signaling Pathway	Ovarian Follicle Development Translational Initiation Regulation Of Translational Initiation Central Nervous System Development Response To Heat Response To Glucose Oligodendrocyte Development Myelination Response To Peptide Hormone T Cell Receptor Signaling Pathway
Pathways		Recycling of eIF2:GDP	Recycling of eIF2:GDP
Drugs
Diseases		Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)	Leukoencephalopathy with vanishing white matter; Vanishing white matter disease; Childhood ataxia with diffuse central nervous system hypomyelination (CACH); Cree leukoencephalopathy (CLE)
GWAS			Mood instability ( 29187730)
Interacting Genes		3 interacting genes: EIF2B2 EIF2S1 EIF2S2	12 interacting genes: APP C9orf72 CCT3 CSNK2A2 EIF2B1 EIF2B4 EIF2B5 EIF2S1 MRFAP1L1 NCK1 NPC2 PCGF6
Entrez ID		8890	8892
HPRD ID		09459	05923
Ensembl ID		ENSG00000115211	ENSG00000119718
Uniprot IDs		B4DUP5 E7ERK9 F8W8L6 Q71US4 Q9HBP7 Q9UI10	P49770 Q53XC2
PDB IDs		6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z	6CAJ 6EZO 6K71 6K72 6O81 6O85 6O9Z
Enriched GO Terms of Interacting Partners?
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