HYAL2 and KRTAP3-2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		HYAL2	KRTAP3-2
Description		hyaluronidase 2	keratin associated protein 3-2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Lysosome Endoplasmic Reticulum Cytosol Plasma Membrane Microvillus Cell Surface Apical Plasma Membrane Endocytic Vesicle Anchored Component Of External Side Of Plasma Membrane Cytoplasmic Vesicle Membrane Raft Anchored Component Of Plasma Membrane Perinuclear Region Of Cytoplasm RNA Polymerase II Transcription Factor Complex	Cytosol Keratin Filament
	Molecular Function	Virus Receptor Activity Transcription Coactivator Activity Hyalurononglucosaminidase Activity Protein Binding Hyaluronic Acid Binding Enzyme Binding Receptor Signaling Protein Tyrosine Kinase Inhibitor Activity Receptor Tyrosine Kinase Binding Hyaluronoglucuronidase Activity Transforming Growth Factor Beta Binding	Structural Molecule Activity Protein Binding
	Biological Process	Response To Reactive Oxygen Species Kidney Development Hematopoietic Progenitor Cell Differentiation Carbohydrate Metabolic Process Glycosaminoglycan Catabolic Process Response To Virus Multicellular Organism Aging Negative Regulation Of Fibroblast Migration Fusion Of Virus Membrane With Host Plasma Membrane Transformation Of Host Cell By Virus Hyaluronan Catabolic Process Negative Regulation Of Cell Growth Positive Regulation Of Urine Volume Monocyte Activation Positive Regulation Of Protein Import Into Nucleus Negative Regulation Of MAP Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Transcription By RNA Polymerase II Response To Antibiotic Viral Entry Into Host Cell Skeletal System Morphogenesis Positive Regulation Of Inflammatory Response Cartilage Development Defense Response To Virus Negative Regulation Of Protein Kinase B Signaling Multicellular Organismal Iron Ion Homeostasis Negative Regulation Of Protein Tyrosine Kinase Activity Renal Water Absorption Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To UV-B Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Interleukin-8 Secretion Positive Regulation Of Interleukin-6 Secretion Positive Regulation Of Extrinsic Apoptotic Signaling Pathway	Keratinization
Pathways		Hyaluronan uptake and degradation	Keratinization
Drugs
Diseases
GWAS		Body mass index ( 26426971) Sleep duration (short sleep) ( 30846698)
Interacting Genes		8 interacting genes: FHL3 KRTAP10-3 KRTAP3-2 MST1R SMAD2 SMAD3 SMAD4 WWOX	30 interacting genes: ARFGAP1 C5orf60 CNNM3 CREB5 DHRS1 GAD1 GATA1 HOXA1 HYAL2 KIF25-AS1 KRTAP10-1 KRTAP10-5 KRTAP12-2 KRTAP26-1 KRTAP4-12 KRTAP9-2 LCE1B LCE2A LCE3C LCE3E LCE4A MAPKBP1 NTM NUFIP2 OTX1 R3HDM2 TBC1D16 TRIM42 TRIP13 YIPF3
Entrez ID		8692	83897
HPRD ID		04649	13938
Ensembl ID		ENSG00000068001	ENSG00000212900
Uniprot IDs		Q12891	Q9BYR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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