VAMP4 and DNAJC5

Number of citations of the paper that reports this interaction (PubMedID 29997244)
3

Data Source:
BioGRID (fluorescent resonance energy transfer)

		VAMP4	DNAJC5
Description		vesicle associated membrane protein 4	DnaJ heat shock protein family (Hsp40) member C5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Lysosome Endosome Golgi Apparatus Plasma Membrane Cell Surface Transport Vesicle Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Trans-Golgi Network Membrane	Mitochondrion Lysosomal Membrane Plasma Membrane Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding	Protein Binding ATP-dependent Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization ER To Golgi Vesicle-mediated Transport Synaptic Vesicle To Endosome Fusion SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Membrane Organization Golgi Ribbon Formation Regulation Of Synaptic Vesicle Endocytosis	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways		Retrograde transport at the Trans-Golgi-Network Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis	Neutrophil degranulation GABA synthesis, release, reuptake and degradation
Drugs
Diseases
GWAS		Cognitive decline rate in late mild cognitive impairment ( 26252872) Hippocampal atrophy ( 25625606) Metabolite levels ( 23823483) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Prostate cancer ( 23535732)
Interacting Genes		11 interacting genes: AP1M1 BCL2L13 CSNK2A1 DNAJC5 KASH5 LMNA PACS1 SNAP29 STX16 STX4 STX6	56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		8674	80331
HPRD ID		06070	08539
Ensembl ID		ENSG00000117533	ENSG00000101152
Uniprot IDs		O75379 Q6IAZ3	Q6AHX3 Q9H3Z4
PDB IDs			2N04 2N05
Enriched GO Terms of Interacting Partners?
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