DNAJC5 and CADM1

Number of citations of the paper that reports this interaction (PubMedID 29997244)
3

Data Source:
BioGRID (fluorescent resonance energy transfer)

		DNAJC5	CADM1
Description		DnaJ heat shock protein family (Hsp40) member C5	cell adhesion molecule 1
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GO Annotations	Cellular Component	Mitochondrion Lysosomal Membrane Plasma Membrane Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane	Plasma Membrane Cell-cell Junction Integral Component Of Membrane Basolateral Plasma Membrane Synapse
	Molecular Function	Protein Binding ATP-dependent Protein Binding	Signaling Receptor Binding Protein Binding PDZ Domain Binding Protein Homodimerization Activity
	Biological Process	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle	T Cell Mediated Cytotoxicity Apoptotic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Multicellular Organism Development Spermatogenesis Cell Recognition Viral Process Cell Differentiation Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Cytokine Secretion Activated T Cell Proliferation Detection Of Stimulus
Pathways		Neutrophil degranulation GABA synthesis, release, reuptake and degradation	Adherens junctions interactions Nectin/Necl trans heterodimerization
Drugs
Diseases			Nasopharyngeal cancer
GWAS		Prostate cancer ( 23535732)	Anorexia nervosa ( 31308545) Body mass index ( 28552196 28892062 25673413) Cardiovascular risk factors (age interaction) ( 20838585) Chronotype ( 30696823) Coffee consumption ( 31046077) Cutaneous squamous cell carcinoma ( 27424798) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Heel bone mineral density ( 30598549 28869591) Menarche (age at onset) ( 27182965 25231870) Obesity-related traits ( 23251661) Thyroid stimulating hormone levels ( 30367059) Type 2 diabetes (age of onset) ( 28060188) Waist circumference ( 28552196)
Interacting Genes		56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7	8 interacting genes: ATF7IP CASK DNAJC5 EPB41L3 HYOU1 MPP3 PSMA6 SDCBP
Entrez ID		80331	23705
HPRD ID		08539	05746
Ensembl ID		ENSG00000101152	ENSG00000182985
Uniprot IDs		Q6AHX3 Q9H3Z4	A0A4Z1 Q9BY67 X5D7A8 X5D8W0 X5DQR8 X5DQS5
PDB IDs		2N04 2N05	3BIN 4H5S
Enriched GO Terms of Interacting Partners?
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