CADPS and DNAJC5

Number of citations of the paper that reports this interaction (PubMedID 29997244)
3

Data Source:
BioGRID (fluorescent resonance energy transfer)

		CADPS	DNAJC5
Description		calcium dependent secretion activator	DnaJ heat shock protein family (Hsp40) member C5
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GO Annotations	Cellular Component	Cytosol Cell Junction Presynapse Glutamatergic Synapse Neuronal Dense Core Vesicle Membrane	Mitochondrion Lysosomal Membrane Plasma Membrane Membrane Neuromuscular Junction Azurophil Granule Membrane Specific Granule Membrane Melanosome Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding Lipid Binding Protein Kinase Binding Metal Ion Binding	Protein Binding ATP-dependent Protein Binding
	Biological Process	Exocytosis Protein Transport Synaptic Vesicle Exocytosis Positive Regulation Of Exocytosis Dense Core Granule Exocytosis	Exocytosis Neurotransmitter Secretion Synaptic Vesicle Exocytosis Neutrophil Degranulation Negative Regulation Of Neuron Apoptotic Process Regulated Exocytosis Chaperone-mediated Protein Folding Regulation Of Synaptic Vesicle Cycle
Pathways			Neutrophil degranulation GABA synthesis, release, reuptake and degradation
Drugs		Calcium Citrate Calcium Phosphate
Diseases
GWAS		Autism spectrum disorder ( 30804558) Breast size ( 22747683 27182965) Cognitive decline rate in late mild cognitive impairment ( 26252872) Economic and political preferences (environmentalism) ( 22566634) Hand grip strength ( 29691431) Lung function (FEV1/FVC) ( 30061609) Metabolite levels (X-11787) ( 23934736) Obsessive-compulsive symptoms ( 26859814) Optic disc size ( 31809533) Pre-treatment viral load in HIV-1 infection ( 31219150) QT interval (sulfonylurea treatment interaction) ( 27958378) Risk-taking tendency (4-domain principal component model) ( 30643258) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Trunk fat mass ( 28552196)	Prostate cancer ( 23535732)
Interacting Genes		15 interacting genes: C17orf67 DMD DNAJC5 DRD2 FAM161A FAM9B KIAA1549 LUC7L2 PIP5K1A SDCBP SHFL TCL1A TTLL10 ZNF572 ZNF688	56 interacting genes: AGFG1 AP2B1 ARHGEF15 BTC CADM1 CADPS CASK CD2 CFTR CGB5 CLCN3 EFNB1 ERC1 FAS FCHO1 GRM8 HBA2 HGS KHDC4 LIN7A LIN7C NECAP1 NRXN3 NUMB PPFIA1 PPFIA4 PRKACA PRKCG PRRC2B PSMD12 RABGEF1 RBSN SCAMP1 SCAMP3 SCAMP5 SH3GL3 SLC17A8 SLC18A2 SLC30A3 SLC32A1 SNAP29 SNAP91 SNCA STX12 STX3 STX4 STX6 STX7 SV2A SYT12 SYT5 SYT9 VAMP1 VAMP3 VAMP4 VAMP7
Entrez ID		8618	80331
HPRD ID		05236	08539
Ensembl ID		ENSG00000163618	ENSG00000101152
Uniprot IDs		F1T0E5 Q9ULU8	Q6AHX3 Q9H3Z4
PDB IDs		1WI1	2N04 2N05
Enriched GO Terms of Interacting Partners?
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