KHSRP and KLHL12

Number of citations of the paper that reports this interaction (PubMedID 27899653)
4

Data Source:
BioGRID (enzymatic study)

		KHSRP	KLHL12
Description		KH-type splicing regulatory protein	kelch like family member 12
Image
GO Annotations	Cellular Component	Exosome (RNase Complex) Nucleoplasm Cytosol Cytoplasmic Stress Granule Membrane	Golgi Membrane Cytosol COPII Vesicle Coat COPII-coated ER To Golgi Transport Vesicle Cul3-RING Ubiquitin Ligase Complex Centriolar Satellite Intracellular Membrane-bounded Organelle
	Molecular Function	DNA Binding RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding	Protein Binding Identical Protein Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Regulation Of Transcription, DNA-templated MRNA Processing MRNA Catabolic Process RNA Splicing MiRNA Metabolic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Regulation Of MRNA Stability Negative Regulation Of Nitric Oxide Biosynthetic Process MRNA Transport Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Cellular Response To Cytokine Stimulus Regulation Of MiRNA Metabolic Process	Protein Monoubiquitination ER To Golgi Vesicle-mediated Transport Neural Crest Formation Neural Crest Cell Development Wnt Signaling Pathway COPII Vesicle Coating Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress KSRP (KHSRP) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA	Degradation of DVL
Drugs		Resveratrol Artenimol
Diseases
GWAS
Interacting Genes		15 interacting genes: A1CF APBB1 BACE1 EXOSC2 EXOSC3 GADD45A GCC1 GSK3B HNRNPA1 HNRNPH1 KLHL12 PARN PTBP2 STK3 UBE2I	46 interacting genes: ARAF ATXN1 BAG6 C1QTNF2 CARD10 CCBE1 COL8A1 CPSF6 CRTC3 CUL3 DGCR6 DRD4 DVL2 DVL3 FBXL17 FGD2 FLNA GLYCTK INMT KHSRP KLHL2 KLHL3 LNX1 MED28 MPP1 MRPL10 MTNR1A NDC80 NTAQ1 PDGFRB PEA15 PEF1 PRR13 RIT1 RPP25L SDCBP SEC31A SNX20 SYNE4 TAOK2 TBC1D10C TTBK2 UBE2I VEGFB VTA1 ZBP1
Entrez ID		8570	59349
HPRD ID		10350	13925
Ensembl ID		ENSG00000088247	ENSG00000117153
Uniprot IDs		Q92945	Q53G59 Q9H7R2
PDB IDs		2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T	2VPJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?