KHSRP and HNRNPH1

Number of citations of the paper that reports this interaction (PubMedID 17643375)
195

Data Source:
BioGRID (pull down, affinity chromatography technology)

		KHSRP	HNRNPH1
Description		KH-type splicing regulatory protein	heterogeneous nuclear ribonucleoprotein H1
Image
GO Annotations	Cellular Component	Exosome (RNase Complex) Nucleoplasm Cytosol Cytoplasmic Stress Granule Membrane	Nucleus Nucleoplasm Cytosol Membrane Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding	RNA Binding Protein Binding Poly(U) RNA Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Regulation Of Transcription, DNA-templated MRNA Processing MRNA Catabolic Process RNA Splicing MiRNA Metabolic Process Negative Regulation Of Low-density Lipoprotein Particle Clearance Regulation Of MRNA Stability Negative Regulation Of Nitric Oxide Biosynthetic Process MRNA Transport Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Cellular Response To Cytokine Stimulus Regulation Of MiRNA Metabolic Process	MRNA Splicing, Via Spliceosome RNA Processing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Regulation Of RNA Splicing
Pathways		ATF4 activates genes in response to endoplasmic reticulum stress KSRP (KHSRP) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs		Resveratrol Artenimol	Copper
Diseases
GWAS			Daytime sleep phenotypes ( 27126917)
Interacting Genes		15 interacting genes: A1CF APBB1 BACE1 EXOSC2 EXOSC3 GADD45A GCC1 GSK3B HNRNPA1 HNRNPH1 KLHL12 PARN PTBP2 STK3 UBE2I	23 interacting genes: APBB1 CRMP1 DDX5 ERG HIPK3 HNRNPF HNRNPH3 KHSRP MTNR1A NCBP1 NCBP2 NDRG1 PIN1 RALY SF1 SF3B4 SREK1 SUMO2 SUMO4 TCERG1 TOM1L1 YWHAG YWHAQ
Entrez ID		8570	3187
HPRD ID		10350	03021
Ensembl ID		ENSG00000088247	ENSG00000169045
Uniprot IDs		Q92945	A0A384MEJ3 P31943
PDB IDs		2HH2 2HH3 2JVZ 2OPU 2OPV 4B8T	2LXU 6DHS
Enriched GO Terms of Interacting Partners?
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