BLZF1 and AKAP9

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		BLZF1	AKAP9
Description		basic leucine zipper nuclear factor 1	A-kinase anchoring protein 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Golgi Apparatus	Golgi Apparatus Golgi Stack Cis-Golgi Network Centrosome Cytosol Cytoskeleton Voltage-gated Potassium Channel Complex Neuronal Cell Body Intracellular Membrane-bounded Organelle Dendritic Branch Synaptic Membrane Glutamatergic Synapse Extrinsic Component Of Postsynaptic Density Membrane
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding	DNA Binding Signaling Receptor Binding Protein Binding Potassium Channel Regulator Activity Protein Kinase A Regulatory Subunit Binding Ion Channel Binding Molecular Adaptor Activity
	Biological Process	Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Golgi Organization Golgi To Plasma Membrane Protein Transport	G2/M Transition Of Mitotic Cell Cycle Microtubule Nucleation Signal Transduction Negative Regulation Of Adenylate Cyclase Activity Chemical Synaptic Transmission Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Microtubule Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Response To Electrical Stimulus Maintenance Of Centrosome Location Regulation Of Membrane Repolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Cardiac Conduction Cellular Response To CAMP Regulation Of Heart Rate By Cardiac Conduction Ciliary Basal Body-plasma Membrane Docking Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Postsynaptic Neurotransmitter Receptor Activity Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Golgi Organization
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Phase 3 - rapid repolarisation Phase 2 - plateau phase Anchoring of the basal body to the plasma membrane Signaling by BRAF and RAF fusions AURKA Activation by TPX2
Drugs
Diseases			Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS			Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Breast cancer ( 29059683) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid t-tau levels in mild cognitive impairment ( 29274321) Disrupted circadian rhythm (low relative amplitude of rest-activity cycles) ( 30120083) Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		52 interacting genes: AKAP9 AMOTL2 BANP BCL6 BEX2 CARD9 CCDC33 CHCHD3 CINP CKS2 DNMT3L EWSR1 FBF1 FHL2 FRMD6 GEM GORASP2 HCLS1 HOXA1 IQUB KDM1A KLHL38 LMO1 LMO2 OAZ3 PRKAB2 PRMT6 PSMA1 PTPN11 RAB2A RAB2B RAB39A RANBP3 RHOJ SCNM1 SELENOS SMAD3 SMARCB1 SRA1 SSX2 SUV39H2 TBC1D7 TRAPPC2L TSC22D4 TXNDC5 VPS28 ZBTB24 ZGPAT ZMAT1 ZNF410 ZNF688 ZZZ3	67 interacting genes: ASB4 BLZF1 C1orf94 CALM1 CALM2 CALM3 CASK CCP110 CDC5L CEP55 CLIC1 CSNK1D CSNK1E CTBP1 DVL2 FMR1 FNBP1 FXR2 GATAD1 GPC4 GRIN1 GTSE1 HNRNPM IKZF3 KCNQ1 KDM1A KIF19 KLC4 MAGEA6 MAGED1 MED1 MYO5A NDEL1 PARD6G PCM1 PCNT PKN1 PKP2 PPP1CA PPP2R1B PPP2R3A PRC1 PRDM14 PRKAR2A PRKAR2B PRKCE RBM10 RBM14 RPA2 SAMD3 SF3B2 SGCE SLAIN1 SSX2 SUV39H2 TACC3 TDP2 THAP1 TNIK TRIP10 TSG101 TSNAX TUBGCP3 USHBP1 USO1 WAC YWHAE
Entrez ID		8548	10142
HPRD ID		16367	04921
Ensembl ID		ENSG00000117475	ENSG00000127914
Uniprot IDs		Q9H2G9	Q5GIA7 Q6PJH3 Q99996
PDB IDs
Enriched GO Terms of Interacting Partners?
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