LMO4 and MTA1

Number of citations of the paper that reports this interaction (PubMedID 16288053)
27

Data Source:
BioGRID (pull down, pull down, affinity chromatography technology)

		LMO4	MTA1
Description		LIM domain only 4	metastasis associated 1
Image
GO Annotations	Cellular Component	Transcription Factor Complex Cell Leading Edge	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Microtubule NuRD Complex Intracellular Membrane-bounded Organelle
	Molecular Function	Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Histone Deacetylase Binding
	Biological Process	Neural Tube Closure Ventricular Septum Development Transcription By RNA Polymerase II Ventral Spinal Cord Interneuron Differentiation Spinal Cord Motor Neuron Differentiation Spinal Cord Association Neuron Differentiation Regulation Of Cell Migration Negative Regulation Of Protein Complex Assembly Positive Regulation Of Kinase Activity Regulation Of Cell Fate Specification Positive Regulation Of Transcription By RNA Polymerase II Thymus Development Regulation Of Cell Activation	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Signal Transduction Response To Ionizing Radiation Histone Deacetylation Circadian Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Locomotor Rhythm Positive Regulation Of Protein Autoubiquitination Positive Regulation Of Nucleic Acid-templated Transcription
Pathways			HDACs deacetylate histones SUMOylation of transcription factors ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Breast cancer ( 27354352) Eosinophil counts ( 29403010) Gait rhythm ( 26219847) Glaucoma (primary open-angle) ( 29891935) Photic sneeze reflex ( 27182965) Prostate-specific antigen levels ( 28139693) Response to TNF antagonist treatment ( 18615156) Resting heart rate ( 27798624) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)	Heel bone mineral density ( 30598549)
Interacting Genes		53 interacting genes: AMOT AMOTL2 BANP BRCA1 CALCOCO2 CCDC102B CEP170P1 CSNK2B DDB1 DEAF1 ERCC6L GABPB1 GADD45A GOLGA2 GRHL2 GSK3B ITSN1 KANK2 KIAA1958 KIF3B KPNA1 KRT15 KRT31 KRT40 LDB1 LDB2 MERTK MTA1 NFYC NHLH1 NONO PDE4DIP PITPNB PLK1 PPARG RBBP8 RBPMS RPS6KA6 SEC24D SMAD4 SMAD9 TCF21 TCF4 TFIP11 TINAGL1 TLE5 TNFSF11 TP53BP2 TSEN15 VPS52 ZBTB43 ZNF397 ZNF675	38 interacting genes: BCL11A BLOC1S1 CCNH CSNK1G2 DDX18 DYNLL1 E2F1 ESR1 FHL3 GPR183 GRB2 H3-4 HDAC1 HDAC2 HIF1A ITGB3BP JUN KHDRBS2 KRT40 KRTAP10-8 LMO4 LRRK2 LZTS2 MAGEA11 MBD3L2 MNAT1 NACC2 NELFCD NOTCH2NLA RBBP4 SAT1 SH3GL1 SH3GLB1 SUMO2 TEX11 TP53 TRIM25 UBE2I
Entrez ID		8543	9112
HPRD ID		09122	04633
Ensembl ID		ENSG00000143013	ENSG00000182979
Uniprot IDs		P61968	Q13330 Q9BRL8
PDB IDs		2L4Z	4BKX 4PBY 4PBZ 4PC0 5FXY 5ICN 6G16
Enriched GO Terms of Interacting Partners?
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