MTA1 and SH3GLB1

Number of citations of the paper that reports this interaction (PubMedID 15978591)
7

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		MTA1	SH3GLB1
Description		metastasis associated 1	SH3 domain containing GRB2 like, endophilin B1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Microtubule NuRD Complex Intracellular Membrane-bounded Organelle	Golgi Membrane Autophagosome Membrane Cytoplasm Mitochondrial Outer Membrane Cytosol Midbody Cytoplasmic Vesicle Protein-containing Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Histone Deacetylase Binding	Protein Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Signal Transduction Response To Ionizing Radiation Histone Deacetylation Circadian Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Locomotor Rhythm Positive Regulation Of Protein Autoubiquitination Positive Regulation Of Nucleic Acid-templated Transcription	Autophagy Apoptotic Process Positive Regulation Of Autophagy Regulation Of Macroautophagy Positive Regulation Of Protein Complex Assembly Regulation Of Protein Stability Regulation Of Cytokinesis Receptor Catabolic Process Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Autophagic Cell Death Membrane Fission Positive Regulation Of Membrane Tubulation Protein Localization To Vacuolar Membrane Positive Regulation Of Protein Targeting To Mitochondrion Positive Regulation Of Autophagosome Assembly
Pathways		HDACs deacetylate histones SUMOylation of transcription factors ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549)
Interacting Genes		38 interacting genes: BCL11A BLOC1S1 CCNH CSNK1G2 DDX18 DYNLL1 E2F1 ESR1 FHL3 GPR183 GRB2 H3-4 HDAC1 HDAC2 HIF1A ITGB3BP JUN KHDRBS2 KRT40 KRTAP10-8 LMO4 LRRK2 LZTS2 MAGEA11 MBD3L2 MNAT1 NACC2 NELFCD NOTCH2NLA RBBP4 SAT1 SH3GL1 SH3GLB1 SUMO2 TEX11 TP53 TRIM25 UBE2I	26 interacting genes: ADAM15 ADAM9 AMPH APP ARHGAP17 BAX BIN1 CDKN2D CMTM5 COQ8A CSDE1 DNM2 EXOSC5 FUNDC1 GADD45A GADD45G HTATIP2 HTT MTA1 PSMA1 SH3GLB2 SH3KBP1 SYNJ1 TFIP11 TPD52L2 ZNF576
Entrez ID		9112	51100
HPRD ID		04633	15333
Ensembl ID		ENSG00000182979	ENSG00000097033
Uniprot IDs		Q13330 Q9BRL8	A0A087WW40 A0A140VJU5 Q9Y371
PDB IDs		4BKX 4PBY 4PBZ 4PC0 5FXY 5ICN 6G16
Enriched GO Terms of Interacting Partners?
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