OFD1 and NME7

Number of citations of the paper that reports this interaction (PubMedID 26638075)
122

Data Source:
BioGRID (proximity labelling technology, two hybrid)

		OFD1	NME7
Description		OFD1 centriole and centriolar satellite protein	NME/NM23 family member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Centrosome Centriole Cytosol Cilium Membrane Centriolar Satellite Ciliary Basal Body	Centrosome Cytosol
	Molecular Function	Protein Binding Identical Protein Binding Alpha-tubulin Binding Gamma-tubulin Binding	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Centriole Replication Regulation Of G2/M Transition Of Mitotic Cell Cycle Axoneme Assembly Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Mitotic Spindle Assembly Ciliary Basal Body-plasma Membrane Docking	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases		Oral-facial-digital syndrome 1 Joubert syndrome
GWAS			Coronary artery disease ( 29212778) D-dimer levels ( 21502573) Pulse pressure ( 27841878 30578418) QT interval ( 30679814) Systolic blood pressure ( 27841878 30578418) Venous thromboembolism ( 21980494 22672568)
Interacting Genes		8 interacting genes: CCSER2 CEP126 EIF6 GPRASP1 LUC7L2 NME7 RUVBL1 S100A6	28 interacting genes: C1orf189 CCHCR1 CDC42EP2 CEP72 DDX1 FKBP6 FOSL1 GOLGA2 IKZF1 KRT18 LNX1 MAP4K4 MYOT NAB2 NEFL NT5C2 OFD1 REL SHTN1 SYCE1 TCF4 TCHP TNIP1 TRIM27 TUFT1 YWHAQ ZBTB48 ZNF263
Entrez ID		8481	29922
HPRD ID		02162	11394
Ensembl ID		ENSG00000046651	ENSG00000143156
Uniprot IDs		A6NF31 E9KL37 O75665	A0A024R8Z7 Q9Y5B8
PDB IDs
Enriched GO Terms of Interacting Partners?
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