NME7 and CDC42EP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		NME7	CDC42EP2
Description		NME/NM23 family member 7	CDC42 effector protein 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Centrosome Cytosol	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle
	Molecular Function	Nucleoside Diphosphate Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Opioid Peptide Activity GTPase Activator Activity Protein Binding GTP-Rho Binding
	Biological Process	Nucleoside Diphosphate Phosphorylation GTP Biosynthetic Process UTP Biosynthetic Process CTP Biosynthetic Process	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein Complex Assembly Positive Regulation Of GTPase Activity Cellular Response To Interferon-gamma
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	MAPK6/MAPK4 signaling
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) D-dimer levels ( 21502573) Pulse pressure ( 27841878 30578418) QT interval ( 30679814) Systolic blood pressure ( 27841878 30578418) Venous thromboembolism ( 21980494 22672568)	Acne (severe) ( 24927181) Mean corpuscular volume ( 27863252)
Interacting Genes		28 interacting genes: C1orf189 CCHCR1 CDC42EP2 CEP72 DDX1 FKBP6 FOSL1 GOLGA2 IKZF1 KRT18 LNX1 MAP4K4 MYOT NAB2 NEFL NT5C2 OFD1 REL SHTN1 SYCE1 TCF4 TCHP TNIP1 TRIM27 TUFT1 YWHAQ ZBTB48 ZNF263	7 interacting genes: ARHGAP26 CDC42 NME7 RHOQ SEPTIN6 SEPTIN7 SNCA
Entrez ID		29922	10435
HPRD ID		11394	09363
Ensembl ID		ENSG00000143156	ENSG00000149798
Uniprot IDs		A0A024R8Z7 Q9Y5B8	O14613
PDB IDs
Enriched GO Terms of Interacting Partners?
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