RASSF5 and AMOTL2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		RASSF5	AMOTL2
Description		Ras association domain family member 5	angiomotin like 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule	Cytosol Plasma Membrane Bicellular Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	Protein Binding Ras GTPase Binding Metal Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Apoptotic Process Negative Regulation Of Cell Proliferation Positive Regulation Of Protein Ubiquitination Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Protein Localization To Nucleus	Angiogenesis Establishment Of Cell Polarity Involved In Ameboidal Cell Migration Wnt Signaling Pathway Actin Cytoskeleton Organization Regulation Of Cell Migration Hippo Signaling
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233) Late-onset Alzheimer's disease ( 27770636) Neurofibrillary tangles ( 25188341)	Cadmium levels ( 26025379) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
Interacting Genes		30 interacting genes: ADH6 AMOTL2 APPBP2 BTRC HRAS ITCH KRAS KRT40 KRTAP4-2 LSM7 MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 VPS28	57 interacting genes: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CHCHD3 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FBXO7 FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MTNR1A MYO5B NDC80 NFIL3 NTAQ1 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPOP SPP1 THRA TMCC2 TNKS2 TRAF2 TRIM27 ZBED1 ZGPAT
Entrez ID		83593	51421
HPRD ID		06117	16485
Ensembl ID		ENSG00000266094	ENSG00000114019
Uniprot IDs		A8K5F3 Q8WWW0	Q9Y2J4
PDB IDs		4LGD 4OH8
Enriched GO Terms of Interacting Partners?
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