CDC7 and CSDE1

		CDC7	CSDE1
Description		cell division cycle 7	cold shock domain containing E1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Intercellular Bridge Mitotic Spindle	Golgi Apparatus Cytosol Plasma Membrane CRD-mediated MRNA Stability Complex
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Metal Ion Binding	RNA Binding Protein Binding
	Biological Process	G1/S Transition Of Mitotic Cell Cycle Double-strand Break Repair Via Break-induced Replication DNA Replication Positive Regulation Of Cell Proliferation Positive Regulation Of Nuclear Cell Cycle DNA Replication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Cell Cycle Phase Transition Cell Division Negative Regulation Of G0 To G1 Transition	Male Gonad Development Nuclear-transcribed MRNA Catabolic Process, No-go Decay
Pathways		Activation of ATR in response to replication stress Activation of the pre-replicative complex Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 27863252) Gestational age at birth (maternal effect) ( 28877031) Glaucoma (primary open-angle) ( 25861811) Lung function (FEV1/FVC) ( 28166213) Lung function (FVC) ( 26635082) Optic disc area ( 25631615 31798171 28073927 21307088) Optic disc parameters ( 20548946) Optic disc size ( 31809533) Optic nerve measurement (cup-to-disc ratio) ( 28061514) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Vertical cup-disc ratio ( 31798171 25241763 28073927) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Autism ( 24189344)
Interacting Genes		26 interacting genes: APP CDK2 CDK4 CDK9 CDKN1A CDKN2A CHAF1A CLSPN CSDE1 DBF4 DBF4B DIAPH1 DTD1 GPT GRHPR MCM10 MCM2 MCM3 MCM4 MCM5 MCM6 MCM7 ORC1 ORC5 ORC6 TOB1	22 interacting genes: C11orf68 CDC7 CTBS DOK1 DPYD FAM9B GCKR GCNT1 GFI1 HID1 HNRNPD IGFBP5 KCNMB4 PABPC1 PCSK7 SH3GLB1 SLIT2 SNRPB2 STT3A SYNCRIP WFS1 WNK1
Entrez ID		8317	7812
HPRD ID		10345	15949
Ensembl ID		ENSG00000097046	ENSG00000009307
Uniprot IDs		A0A384MTU6 B2R6V2 O00311	A0A024R0E2 A0A024R0K2 O75534
PDB IDs		4F99 4F9A 4F9B 4F9C 5UWQ 5UWR	1WFQ 1X65 2YTV 2YTX 2YTY
Enriched GO Terms of Interacting Partners?
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