TAF15 and SMARCC2

Number of citations of the paper that reports this interaction (PubMedID 30962207)
2

Data Source:
BioGRID (pull down)

		TAF15	SMARCC2
Description		TATA-box binding protein associated factor 15	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	DNA Binding Transcription Coregulator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Metal Ion Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding
	Biological Process	Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter RNA Splicing Positive Regulation Of Transcription, DNA-templated MRNA Stabilization Regulation Of Signal Transduction By P53 Class Mediator	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases		Extraskeletal myxoid chondrosarcoma
GWAS		Blood protein levels ( 28240269) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	Asthma ( 31619474)
Interacting Genes		22 interacting genes: ARID1A CACNA1A H2AC20 H3-4 H3C1 H4C14 POLR2C POLR2E POLR2G PRMT8 SAFB SF1 SMARCA4 SMARCC1 SMARCC2 TAF1 TAF12 TAF13 TAF5 TAF7 YWHAG ZNF384	25 interacting genes: ARF6 ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TAF15 TERF1 TERF2IP
Entrez ID		8148	6601
HPRD ID		09031	03437
Ensembl ID		ENSG00000270647	ENSG00000139613
Uniprot IDs		Q92804	A0A024RB22 F8VXC8 Q8TAQ2
PDB IDs		2MMY
Enriched GO Terms of Interacting Partners?
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