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SMARCC2

Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Image No pdb structure
GO Annotations Cellular Component
  • Nuclear Chromatin
  • Nucleoplasm
  • SWI/SNF Complex
  • Protein-containing Complex
  • NpBAF Complex
  • NBAF Complex
Molecular Function
  • RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
  • Transcription Coactivator Activity
  • Protein Binding
  • Nucleosomal DNA Binding
  • Histone Binding
Biological Process
  • Nucleosome Disassembly
  • Chromatin Remodeling
  • Regulation Of Transcription By RNA Polymerase II
  • Nervous System Development
  • ATP-dependent Chromatin Remodeling
  • Negative Regulation Of Transcription, DNA-templated
  • Positive Regulation Of Transcription, DNA-templated
Pathways
  • RMTs methylate histone arginines
  • RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS
  • Asthma ( 31619474)
Interacting Genes 25 interacting genes: ARF6 ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TAF15 TERF1 TERF2IP
Entrez ID 6601
HPRD ID 03437
Ensembl ID ENSG00000139613
Uniprot IDs A0A024RB22 F8VXC8 Q8TAQ2
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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