SETD7 and DNMT1

  • Number of citations of the paper that reports this interaction (PubMedID 21151116)
  • 78
  • Data Source:
  • BioGRID (enzymatic study)

SETD7

DNMT1

Description SET domain containing 7, histone lysine methyltransferase DNA methyltransferase 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Diastolic blood pressure in combination therapy (beta blocker and thiazide diuretic) ( 29097388)
  • Lean body mass ( 28552196)
  • Salty taste perception in obesity with metabolic syndrome ( 31005965)
  • Serum lycopene concentrations ( 26861389)
Interacting Genes 28 interacting genes: A1BG DNMT1 E2F1 ESR1 H3-3A H3-4 H3C1 H3C14 H4C1 HCFC1 KLF4 L3MBTL1 MDM2 NR2F2 PPP1R12A PRKAR1A RELA RIOK1 SERTAD1 SIL1 SIRT1 SMAD7 SOX2 STAT3 STEAP3 TAF10 TAF7 TP53 40 interacting genes: AKT1 BAZ2A BRAP CBX1 CSNK2B DAXX DCAF5 DMAP1 DNASE2 DNM2 DNMT3A DNMT3B DYNLL1 E2F6 EED ELAVL3 EZH2 GSK3B H3-4 HDAC1 HDAC2 HELLS HMGB1 L3MBTL3 LASP1 MECP2 NRIP1 PCNA PRKAA2 RB1 RGS6 RPS6KA6 RUNX1 RUNX1T1 SETD7 SUV39H1 TRIM27 TSG101 UBB YWHAQ
Entrez ID 80854 1786
HPRD ID 16226 00532
Ensembl ID ENSG00000145391 ENSG00000130816
Uniprot IDs B5MCZ8 D6RJA0 Q8WTS6 I6L9H2 P26358 Q59FP7
PDB IDs 1H3I 1MT6 1MUF 1N6A 1N6C 1O9S 1XQH 2F69 3CBM 3CBO 3CBP 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 3OS5 3VUZ 3VV0 4E47 4J7F 4J7I 4J83 4J8O 4JDS 4JLG 5AYF 5EG2 5YLT 3EPZ 3PTA 3SWR 4WXX 4YOC 4Z96 4Z97 5WVO 5YDR
Enriched GO Terms of Interacting Partners?
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