CPTP and ECM1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CPTP	ECM1
Description		ceramide-1-phosphate transfer protein	extracellular matrix protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Outer Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Membrane	Extracellular Region Extracellular Matrix Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Phospholipid Binding Lipid Binding Ceramide 1-phosphate Binding Ceramide 1-phosphate Transporter Activity	Protease Binding Interleukin-2 Receptor Binding Extracellular Matrix Structural Constituent Protein Binding Protein C-terminus Binding Enzyme Binding Laminin Binding
	Biological Process	Glycosphingolipid Metabolic Process Negative Regulation Of Autophagy Ceramide Transport Glycolipid Transport Negative Regulation Of Interleukin-1 Beta Secretion Intermembrane Lipid Transfer Negative Regulation Of NLRP3 Inflammasome Complex Assembly Ceramide 1-phosphate Transport	Ossification Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cytokine-mediated Signaling Pathway Chondrocyte Development Platelet Degranulation Regulation Of Type 2 Immune Response Endochondral Bone Growth Regulation Of Transcription By RNA Polymerase II Inflammatory Response Signal Transduction Negative Regulation Of Peptidase Activity Negative Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Angiogenesis Regulation Of T Cell Migration
Pathways		Glycosphingolipid metabolism	Platelet degranulation
Drugs
Diseases			Lipoid proteinosis; Urbach-Wiethe disease
GWAS			Blood protein levels ( 30072576 28240269) Migraine ( 27322543) Schizophrenia ( 28991256 30285260)
Interacting Genes		7 interacting genes: CD7 ECM1 ELOC INPP5K PHF13 SMAD3 ZNF451	9 interacting genes: ATN1 BNIP3L CPTP DDIAS FBLN1 HSPG2 IRAK3 RERE SRPK1
Entrez ID		80772	1893
HPRD ID		18878	03727
Ensembl ID		ENSG00000224051	ENSG00000143369
Uniprot IDs		Q5TA50 S4S694	A0A140VJI7 Q16610
PDB IDs		4K80 4K84 4K85 4K8N 4KBS 4KF6
Enriched GO Terms of Interacting Partners?
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