ECM1 and CPTP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ECM1	CPTP
Description		extracellular matrix protein 1	ceramide-1-phosphate transfer protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Matrix Platelet Dense Granule Lumen Collagen-containing Extracellular Matrix Extracellular Exosome	Nuclear Outer Membrane Golgi Apparatus Cytosol Plasma Membrane Endosome Membrane Membrane
	Molecular Function	Protease Binding Interleukin-2 Receptor Binding Extracellular Matrix Structural Constituent Protein Binding Protein C-terminus Binding Enzyme Binding Laminin Binding	Phospholipid Binding Lipid Binding Ceramide 1-phosphate Binding Ceramide 1-phosphate Transporter Activity
	Biological Process	Ossification Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Negative Regulation Of Cytokine-mediated Signaling Pathway Chondrocyte Development Platelet Degranulation Regulation Of Type 2 Immune Response Endochondral Bone Growth Regulation Of Transcription By RNA Polymerase II Inflammatory Response Signal Transduction Negative Regulation Of Peptidase Activity Negative Regulation Of Bone Mineralization Biomineral Tissue Development Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Angiogenesis Regulation Of T Cell Migration	Glycosphingolipid Metabolic Process Negative Regulation Of Autophagy Ceramide Transport Glycolipid Transport Negative Regulation Of Interleukin-1 Beta Secretion Intermembrane Lipid Transfer Negative Regulation Of NLRP3 Inflammasome Complex Assembly Ceramide 1-phosphate Transport
Pathways		Platelet degranulation	Glycosphingolipid metabolism
Drugs
Diseases		Lipoid proteinosis; Urbach-Wiethe disease
GWAS		Blood protein levels ( 30072576 28240269) Migraine ( 27322543) Schizophrenia ( 28991256 30285260)
Interacting Genes		9 interacting genes: ATN1 BNIP3L CPTP DDIAS FBLN1 HSPG2 IRAK3 RERE SRPK1	7 interacting genes: CD7 ECM1 ELOC INPP5K PHF13 SMAD3 ZNF451
Entrez ID		1893	80772
HPRD ID		03727	18878
Ensembl ID		ENSG00000143369	ENSG00000224051
Uniprot IDs		A0A140VJI7 Q16610	Q5TA50 S4S694
PDB IDs			4K80 4K84 4K85 4K8N 4KBS 4KF6
Enriched GO Terms of Interacting Partners?
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