TRAF3IP3 and WAC

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRAF3IP3	WAC
Description		TRAF3 interacting protein 3	WW domain containing adaptor with coiled-coil
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck
	Molecular Function	Protein Binding	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding
	Biological Process		Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Positive Regulation Of Macroautophagy Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Alopecia areata ( 25608926) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252) Worry too long after an embarrassing experience ( 29500382)	Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Multiple myeloma ( 27363682)
Interacting Genes		12 interacting genes: CDCA7L EMD FATE1 KASH5 NDEL1 PSTPIP1 SP100 TFIP11 TRAF3 TRIM36 WAC ZNRD2	20 interacting genes: AKAP9 APP CRKL DYDC1 KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17
Entrez ID		80342	51322
HPRD ID		16305	18291
Ensembl ID		ENSG00000009790	ENSG00000095787
Uniprot IDs		B1AJU2 B3KWQ9 Q9Y228	Q9BTA9
PDB IDs
Enriched GO Terms of Interacting Partners?
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