WAC and TRAF3IP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		WAC	TRAF3IP3
Description		WW domain containing adaptor with coiled-coil	TRAF3 interacting protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck	Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Complex Binding Chromatin Binding Protein Binding	Protein Binding
	Biological Process	Cellular Response To DNA Damage Stimulus Histone Monoubiquitination Positive Regulation Of Macroautophagy Protein Ubiquitination Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process G1 DNA Damage Checkpoint Positive Regulation Of Transcription, DNA-templated Histone H2B Conserved C-terminal Lysine Ubiquitination
Pathways		E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Intraocular pressure ( 29617998) Multiple myeloma ( 27363682)	Alopecia areata ( 25608926) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Red blood cell count ( 27863252) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		20 interacting genes: AKAP9 APP CRKL DYDC1 KLC3 KRT15 LNX1 MOBP MTUS2 NDE1 NFE2L2 POLR2A SYTL5 TRAF1 TRAF3IP1 TRAF3IP3 UBQLN4 VCP VCPIP1 ZDHHC17	12 interacting genes: CDCA7L EMD FATE1 KASH5 NDEL1 PSTPIP1 SP100 TFIP11 TRAF3 TRIM36 WAC ZNRD2
Entrez ID		51322	80342
HPRD ID		18291	16305
Ensembl ID		ENSG00000095787	ENSG00000009790
Uniprot IDs		Q9BTA9	B1AJU2 B3KWQ9 Q9Y228
PDB IDs
Enriched GO Terms of Interacting Partners?
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