GCC1 and PAK5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GCC1	PAK5
Description		GRIP and coiled-coil domain containing 1	p21 (RAC1) activated kinase 5
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Cytosol	Nucleoplasm Cytoplasm Mitochondrion Synapse
	Molecular Function	Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process		Regulation Of Cell Growth Apoptotic Process Cytoskeleton Organization Signal Transduction Regulation Of Mitotic Cell Cycle Learning Memory Locomotory Behavior Cell Proliferation Cell Migration Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Retrograde transport at the Trans-Golgi-Network	Activation of RAC1
Drugs
Diseases
GWAS		Feeling worry ( 29500382) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Medication adherence in chronic diseases ( 25317111) Type 2 diabetes ( 26818947 22158537 30718926)	Atopy ( 28927820) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)
Interacting Genes		44 interacting genes: ABI2 ADGRE5 AMOTL2 APP ARL1 ATF4 ATN1 BIRC2 BRCA1 C1orf94 CCDC85B CEP57 CEP70 COIL CPSF7 CRHR2 DNAJA3 FAM71F2 FBF1 GLI1 GOLGA2 GTF2I HILPDA IKBKG ITSN1 KHSRP KIAA0753 KIAA1217 LZTS2 MCRS1 NAB2 NAV1 NECAB2 NINL OIP5 PAK5 PCDHA1 RBM28 SMARCD1 SPOP TFIP11 TRIM29 USHBP1 ZNF276	21 interacting genes: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FHL3 GCC1 INKA1 LENG1 LZTS2 PDLIM7 PRPF31 PSMF1 RAC1 SORBS3 TUBGCP4 UXT
Entrez ID		79571	57144
HPRD ID		07599	06423
Ensembl ID		ENSG00000179562	ENSG00000101349
Uniprot IDs		A4D0Z4 Q96CN9	B0AZM9 Q9P286
PDB IDs			2F57
Enriched GO Terms of Interacting Partners?
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