ZNF426 and USP25

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZNF426	USP25
Description		zinc finger protein 426	ubiquitin specific peptidase 25
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Endoplasmic Reticulum Cytosol
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Peptidase Activity Ubiquitin-like Protein-specific Protease Activity Ubiquitin Protein Ligase Binding Thiol-dependent Ubiquitinyl Hydrolase Activity Ubiquitin Binding ATPase Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Cellular Protein Modification Process Proteolysis Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination Negative Regulation Of ERAD Pathway
Pathways		Generic Transcription Pathway	Ub-specific processing proteases
Drugs
Diseases
GWAS			Crohn's disease ( 25489960) Metabolite levels ( 23823483) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Panic disorder ( 19165232) Parkinson's disease ( 21738487) QRS complex (12-leadsum) ( 27659466) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		15 interacting genes: CALCOCO2 CCDC85B CEP70 CIB3 EFEMP2 GLRX3 KRTAP4-12 LPXN LZTS2 MDFI MPPE1 MTUS2 NINL TSGA10 USP25	16 interacting genes: ACTA1 FLNC GAPDH MAGEB4 MT2A RAD23A SENP1 SKIL SUMO1 SUMO2 SUMO3 SYK TNKS UBC UBE2I ZNF426
Entrez ID		79088	29761
HPRD ID		15787	05296
Ensembl ID		ENSG00000130818	ENSG00000155313
Uniprot IDs		A0A024R7D7 K7EME3 K7ER43 Q59EH4 Q9BUY5	Q9UHP3
PDB IDs			2MUX 5GP7 5O71 6H4J 6H4K 6HEL 6HEM
Enriched GO Terms of Interacting Partners?
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