ZNF426 and GLRX3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZNF426	GLRX3
Description		zinc finger protein 426	glutaredoxin 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Cell Nucleus Cytosol Cell Cortex Z Disc Dendrite
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	RNA Binding Protein Kinase C Binding Protein Binding Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Identical Protein Binding Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	Regulation Of Transcription, DNA-templated	Regulation Of The Force Of Heart Contraction Cellular Iron Ion Homeostasis Negative Regulation Of Cardiac Muscle Hypertrophy Electron Transport Chain [2Fe-2S] Cluster Assembly Cell Redox Homeostasis Protein Maturation By Iron-sulfur Cluster Transfer
Pathways		Generic Transcription Pathway	Iron uptake and transport
Drugs
Diseases
GWAS			Alcohol dependence ( 26365420) Copper levels ( 26025379) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) HIV-1 susceptibility ( 21160409) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Triglyceride levels x short total sleep time interaction (1df test) ( 31719535) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		15 interacting genes: CALCOCO2 CCDC85B CEP70 CIB3 EFEMP2 GLRX3 KRTAP4-12 LPXN LZTS2 MDFI MPPE1 MTUS2 NINL TSGA10 USP25	69 interacting genes: ADAMTSL4 ALKBH3 BCL6 BOLA1 CA9 CBLB CCHCR1 CGGBP1 CIAPIN1 EFEMP2 FAM118A FRA10AC1 GATA1 GMCL1 GRN HEXD IHO1 IKZF1 KRT31 KRT38 KRTAP1-3 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE2D LNX2 LRIG1 MAP3K3 MAPK6 MAPKBP1 MDFI MOXD1 NADK NOTCH2NLA OLFM3 PCSK5 PFDN5 PLEKHG4B PLSCR1 PRKCQ PRKCZ PRKD2 RGS20 SOX7 STAU1 TCF4 TLE5 TMEM25 TRAF1 TRIM36 TRIM42 UGP2 ZBTB44 ZNF148 ZNF23 ZNF426 ZNF512B ZNF544
Entrez ID		79088	10539
HPRD ID		15787	10153
Ensembl ID		ENSG00000130818	ENSG00000108010
Uniprot IDs		A0A024R7D7 K7EME3 K7ER43 Q59EH4 Q9BUY5	A0A140VJK1 O76003
PDB IDs			2DIY 2WZ9 2YAN 3ZYW
Enriched GO Terms of Interacting Partners?
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