MOGS and ETAA1

		MOGS	ETAA1
Description		mannosyl-oligosaccharide glucosidase	ETAA1 activator of ATR kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome	Nuclear Replication Fork
	Molecular Function	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity	Protein Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process	DNA Repair Cellular Response To DNA Damage Stimulus Replication Fork Processing Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of DNA Damage Checkpoint
Pathways		Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS			Endometriosis ( 28537267) Lung adenocarcinoma ( 28604730) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Male-pattern baldness ( 27182965) Milk allergy ( 25710614) Pancreatic cancer ( 26098869) Periodontitis (CDC/AAP) ( 24024966) Photic sneeze reflex ( 27182965) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415) Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia ( 25710658) Waist-hip ratio ( 23966867) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28430825 28448500)
Interacting Genes		9 interacting genes: C1D CHGB ETAA1 EXOC6B MXD1 PCBP1 RAB11FIP5 REL VPS54	1 interacting genes: MOGS
Entrez ID		7841	54465
HPRD ID		03214	13282
Ensembl ID		ENSG00000115275	ENSG00000143971
Uniprot IDs		A0A384MDR6 Q13724 Q58F09	Q9NY74
PDB IDs
Enriched GO Terms of Interacting Partners?
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