MOGS and C1D

		MOGS	C1D
Description		mannosyl-oligosaccharide glucosidase	C1D nuclear receptor corepressor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Exosome	Nuclear Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytoplasm Transcriptional Repressor Complex
	Molecular Function	Mannosyl-oligosaccharide Glucosidase Activity Glucosidase Activity	DNA Binding Transcription Corepressor Activity RNA Binding Protein Binding Nuclear Receptor Binding
	Biological Process	Protein Folding Protein N-linked Glycosylation Oligosaccharide Metabolic Process	Maturation Of 5.8S RRNA RRNA Processing Apoptotic Process Negative Regulation Of Transcription, DNA-templated
Pathways		Defective MOGS causes MOGS-CDG (CDG-2b) N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type II
GWAS			Familial lung adenocarcinoma ( 29924316) Male-pattern baldness ( 27182965) Obstetric antiphospholipid syndrome ( 28424481) Restless legs syndrome ( 29029846) Systolic blood pressure response to hydrochlorothiazide in hypertension ( 27802415)
Interacting Genes		9 interacting genes: C1D CHGB ETAA1 EXOC6B MXD1 PCBP1 RAB11FIP5 REL VPS54	12 interacting genes: APP IL23R MOGS NCOR1 NCOR2 NR1D1 PCBD2 PRKDC SASH1 THRA THRB TSNAX
Entrez ID		7841	10438
HPRD ID		03214	07382
Ensembl ID		ENSG00000115275	ENSG00000197223
Uniprot IDs		A0A384MDR6 Q13724 Q58F09	Q13901
PDB IDs
Enriched GO Terms of Interacting Partners?
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