RPH3AL and RAB3B

Number of citations of the paper that reports this interaction (PubMedID 12578829)
52

Data Source:
HPRD (in vitro, in vivo)

		RPH3AL	RAB3B
Description		rabphilin 3A like (without C2 domains)	RAB3B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane	Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Secretory Granule Cytoplasmic Vesicle Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Dopaminergic Synapse Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Rab GTPase Binding LIM Domain Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Insulin Secretion Response To Drug Glucose Homeostasis Negative Regulation Of G Protein-coupled Receptor Signaling Pathway	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Plasma Membrane Regulation Of Vesicle Size Regulation Of Synaptic Vesicle Cycle
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS		AIDS progression ( 21502085) Dimensional psychopathology (Cognitive) ( 29496196) Idiopathic intracranial hypertension ( 29608535) Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)
Interacting Genes		13 interacting genes: MID2 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 TCEA3 UNC13B ZYX	13 interacting genes: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RIMS2 RPH3A RPH3AL SMAD1 SMAD4 TGFBR1
Entrez ID		9501	5865
HPRD ID		05345	01540
Ensembl ID		ENSG00000181031	ENSG00000169213
Uniprot IDs		A8K7D5 Q9UNE2	P20337
PDB IDs			3DZ8
Enriched GO Terms of Interacting Partners?
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