SLC30A2 and CCL4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SLC30A2	CCL4
Description		solute carrier family 30 member 2	C-C motif chemokine ligand 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosomal Membrane Late Endosome Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Extracellular Region Extracellular Space
	Molecular Function	Zinc Ion Transmembrane Transporter Activity Protein Binding Identical Protein Binding	Cytokine Activity Protein Binding Chemokine Activity CCR1 Chemokine Receptor Binding CCR5 Chemokine Receptor Binding Identical Protein Binding CCR Chemokine Receptor Binding
	Biological Process	Response To Zinc Ion Regulation Of Sequestering Of Zinc Ion Positive Regulation Of Sequestering Of Zinc Ion Zinc Ion Transmembrane Transport	Monocyte Chemotaxis Inflammatory Response Immune Response Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Response To Toxic Substance Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Negative Regulation By Host Of Viral Transcription Lymphocyte Chemotaxis Positive Regulation Of Calcium-mediated Signaling Positive Regulation Of Calcium Ion Transport Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways		Zinc efflux and compartmentalization by the SLC30 family	Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs
Diseases
GWAS			Blood protein levels in cardiovascular risk ( 28369058) Body mass index ( 26426971) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		11 interacting genes: ADAM33 CCL4 CCL4L2 CD99L2 CREB3 KASH5 LMNA LTA PVR SERPING1 TNFRSF12A	8 interacting genes: ACKR2 CCL3 CCR1 CCR3 CCR5 CCR8 CXCL8 SLC30A2
Entrez ID		7780	6351
HPRD ID		18057	01657
Ensembl ID		ENSG00000158014	ENSG00000275302
Uniprot IDs		Q9BRI3	P13236
PDB IDs			1HUM 1HUN 1JE4 2FFK 2FIN 2X6L 3TN2 4RAL
Enriched GO Terms of Interacting Partners?
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