TRPV1 and AKAP5

Number of citations of the paper that reports this interaction (PubMedID 18701070)
93

Data Source:
BioGRID (pull down, pull down)

		TRPV1	AKAP5
Description		transient receptor potential cation channel subfamily V member 1	A-kinase anchoring protein 5
Image		No pdb structure
GO Annotations	Cellular Component	Cell Mitochondrion Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Cell Junction Intrinsic Component Of Plasma Membrane Dendritic Spine Membrane Neuronal Cell Body Postsynaptic Membrane	Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Dendrite Membrane Dendritic Spine Membrane Raft Excitatory Synapse
	Molecular Function	Transmembrane Signaling Receptor Activity Ion Channel Activity Extracellular Ligand-gated Ion Channel Activity Excitatory Extracellular Ligand-gated Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding ATP Binding Calcium-release Channel Activity Chloride Channel Regulator Activity Phosphatidylinositol Binding Identical Protein Binding Metal Ion Binding Phosphoprotein Binding Temperature-gated Ion Channel Activity	Protein Binding Calmodulin Binding Adenylate Cyclase Binding SH3 Domain Binding Protein Phosphatase 2B Binding Beta-2 Adrenergic Receptor Binding Protein Kinase A Regulatory Subunit Binding Glutamate Receptor Binding GABA Receptor Binding Protein Kinase A Binding Molecular Adaptor Activity Scaffold Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Fever Generation Microglial Cell Activation Diet Induced Thermogenesis Peptide Secretion Negative Regulation Of Systemic Arterial Blood Pressure Lipid Metabolic Process Cell Surface Receptor Signaling Pathway Chemosensory Behavior Negative Regulation Of Heart Rate Negative Regulation Of Mitochondrial Membrane Potential Glutamate Secretion Cellular Response To Heat Positive Regulation Of Apoptotic Process Response To Peptide Hormone Positive Regulation Of Nitric Oxide Biosynthetic Process Behavioral Response To Pain Sensory Perception Of Mechanical Stimulus Thermoception Detection Of Temperature Stimulus Involved In Thermoception Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain Detection Of Chemical Stimulus Involved In Sensory Perception Of Pain Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Excitatory Postsynaptic Potential Smooth Muscle Contraction Involved In Micturition Positive Regulation Of Gastric Acid Secretion Calcium Ion Transmembrane Transport Cellular Response To Alkaloid Cellular Response To ATP Cellular Response To Tumor Necrosis Factor Cellular Response To Acidic PH Cellular Response To Temperature Stimulus Negative Regulation Of Establishment Of Blood-brain Barrier Calcium Ion Import Across Plasma Membrane Response To Capsazepine Cellular Response To Nerve Growth Factor Stimulus	Protein Targeting Signal Transduction Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity Chemical Synaptic Transmission Regulation Of Protein Kinase A Signaling Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		TRP channels	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Trafficking of AMPA receptors ROBO receptors bind AKAP5 ROBO receptors bind AKAP5
Drugs		Alpha-Linolenic Acid Icosapent Aspartame Acetaminophen Ricinoleic Acid Capsaicin Zucapsaicin
Diseases
GWAS
Interacting Genes		8 interacting genes: AKAP5 CALM1 EGFR ITCH PRKCE SNAPIN SYT9 TRPV2	14 interacting genes: ADRB2 CALM1 DLG1 DLG4 GABRB1 GABRB3 IQGAP1 KCNJ2 PPP3CA PRKAR2A PRKAR2B PRKCA RET TRPV1
Entrez ID		7442	9495
HPRD ID		03648	05255
Ensembl ID		ENSG00000196689	ENSG00000179841
Uniprot IDs		Q8NER1	P24588 Q6PG46
PDB IDs			2H9R 3LL8 5NIN
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?