TCF20 and RNF4

Number of citations of the paper that reports this interaction (PubMedID 10849425)
11

Data Source:
HPRD (two hybrid, in vitro)

		TCF20	RNF4
Description		transcription factor 20	ring finger protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Body	Nucleus Nucleoplasm Cytoplasm Nuclear Body PML Body Microtubule End
	Molecular Function	DNA Binding DNA-binding Transcription Factor Activity Transcription Coactivator Activity RNA Binding Protein Binding Transcription Regulatory Region DNA Binding Metal Ion Binding	DNA Binding Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity Nucleosome Binding SUMO Polymer Binding Identical Protein Binding Androgen Receptor Binding
	Biological Process	Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Androgen Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Response To Arsenic-containing Substance Protein Autoubiquitination Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Protein K6-linked Ubiquitination Regulation Of Spindle Assembly Regulation Of Kinetochore Assembly
Pathways			Processing of DNA double-strand break ends Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Antisaccade task score ( 31596458) Arterial stiffness ( 31070453) Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 29273807) Chronotype ( 30696823) Cognitive function ( 25644384) Intelligence ( 28530673) Isthmus-cingulate cortex volume ( 31530798) Schizophrenia ( 25056061 29483656 30285260)	Colorectal adenoma (advanced) ( 29228715) Colorectal cancer ( 29228715) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Dimensional psychopathology (Social) ( 29496196) Tourette syndrome ( 30818990)
Interacting Genes		8 interacting genes: AR ESR1 H2AC20 H2BC21 JUN MAPK14 RNF4 SMAD1	39 interacting genes: AR ATXN1 ESR1 GSC2 H3C14 HMGA1 HNF4A IKBKG PATZ1 PGR SKIL SP1 SRPK2 SUMO1 SUMO2 TBP TCF20 TERF2 TRAIP TRIM28 TRPS1 UBC UBE2A UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L6 UBE2N UBE2T UBE2W UEVLD
Entrez ID		6942	6047
HPRD ID		04378	04167
Ensembl ID		ENSG00000100207	ENSG00000063978
Uniprot IDs		Q9UGU0 W5ZR30	P78317
PDB IDs			2EA6 2XEU 4PPE
Enriched GO Terms of Interacting Partners?
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