ELOC and NOTCH4

  • Number of citations of the paper that reports this interaction (PubMedID 22001063)
  • 4
  • Data Source:
  • BioGRID (biochemical, fluorescent resonance energy transfer)

ELOC

NOTCH4

Description elongin C notch receptor 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced glycation end-product levels ( 26083729)
  • Age-related macular degeneration ( 22694956)
  • Aspartate aminotransferase levels ( 29403010)
  • Asthma ( 21804548 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 31043756)
  • Blood protein levels ( 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Chronic hepatitis B infection ( 25802187)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947)
  • Colorectal cancer ( 30529582)
  • Crohn's disease ( 23266558)
  • Epstein-Barr virus immune response (EBNA-1) ( 23326239)
  • Food antigen IgG levels ( 24962563)
  • HIV-1 control ( 20041166)
  • Inflammatory bowel disease ( 28067908)
  • Iron status biomarkers (iron levels) ( 28334935)
  • Joint mobility (Beighton score) ( 27182965)
  • Longevity ( 30294719)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Lupus nephritis in systemic lupus erythematosus ( 24925725)
  • Migraine ( 27322543)
  • Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection ( 25030430)
  • Obesity-related traits ( 23251661)
  • Objective response to lithium treatment in bipolar disorder ( 26503763)
  • Prostate cancer ( 23535732)
  • Reticulocyte fraction of red cells ( 27863252)
  • Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
  • Schizophrenia ( 19571808 30285260 23894747)
  • Squamous cell lung carcinoma ( 28604730)
  • Systemic lupus erythematosus ( 21408207)
  • Systemic sclerosis ( 21779181)
  • Takayasu arteritis ( 25604533)
  • Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
  • Ulcerative colitis ( 24837172 28067908)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 47 interacting genes: CBX5 CENPC COMMD1 CPTP CUL2 CUL3 CYP2J2 ECT2 EFNB3 ELOA2 ELOA3 ELOB EPOR GDAP1 GHR HNF4G ID2 INSIG1 JTB KRT8 LRRC41 LY96 MCM7 MED8 METTL21C MRAS NAA25 NFKBIA NOTCH4 NRCAM PEX2 PRAME RCAN2 RNF7 RPL7 SAT2 SERTAD1 SKAP1 SOCS1 SOCS3 SOCS6 UBC UBE2W USP33 VHL WNT7B ZYG11B 14 interacting genes: DLL4 EGFL7 ELOC FBXW7 MAML1 MAML2 MAML3 NEU1 PSEN1 PSEN2 RBPJ SMAD2 SMAD3 SMAD4
Entrez ID 6921 4855
HPRD ID 02875 01290
Ensembl ID ENSG00000154582 ENSG00000204301
Uniprot IDs A0A024R7Y5 Q15369 A0A1U9X983 Q99466
PDB IDs 1LM8 1LQB 1VCB 2C9W 2IZV 2MA9 3DCG 3ZKJ 3ZNG 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K 4BKS 4BKT 4N9F 4W9C 4W9D 4W9E 4W9F 4W9G 4W9H 4W9I 4W9J 4W9K 4W9L 4WQO 5BO4 5LLI 5N4W 5NVV 5NVW 5NVX 5NVY 5NVZ 5NW0 5NW1 5NW2 5T35 6BVB 6C5X 6FMI 6FMJ 6FMK 6GFX 6GFY 6GFZ 6GMN 6GMQ 6GMR 6GMX 6HAX 6HAY 6HR2 6I4X 6I5J 6I5N 6I7R 6R7F 6R7H 6R7N
Enriched GO Terms of Interacting Partners?
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