NOTCH4 and NEU1

NOTCH4

NEU1

Description notch receptor 4 neuraminidase 1
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Advanced glycation end-product levels ( 26083729)
  • Age-related macular degeneration ( 22694956)
  • Aspartate aminotransferase levels ( 29403010)
  • Asthma ( 21804548 31619474)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 31043756)
  • Blood protein levels ( 28240269)
  • Blood protein levels in cardiovascular risk ( 28369058)
  • Chronic hepatitis B infection ( 25802187)
  • Circulating myeloperoxidase levels (serum) ( 23620142)
  • Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia ( 26876947)
  • Colorectal cancer ( 30529582)
  • Crohn's disease ( 23266558)
  • Epstein-Barr virus immune response (EBNA-1) ( 23326239)
  • Food antigen IgG levels ( 24962563)
  • HIV-1 control ( 20041166)
  • Inflammatory bowel disease ( 28067908)
  • Iron status biomarkers (iron levels) ( 28334935)
  • Joint mobility (Beighton score) ( 27182965)
  • Longevity ( 30294719)
  • Lung cancer ( 28604730)
  • Lung cancer in ever smokers ( 28604730)
  • Lupus nephritis in systemic lupus erythematosus ( 24925725)
  • Migraine ( 27322543)
  • Mixed cryoglobulinemia vasculitis in chronic hepatitis C infection ( 25030430)
  • Obesity-related traits ( 23251661)
  • Objective response to lithium treatment in bipolar disorder ( 26503763)
  • Prostate cancer ( 23535732)
  • Reticulocyte fraction of red cells ( 27863252)
  • Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848)
  • Schizophrenia ( 19571808 30285260 23894747)
  • Squamous cell lung carcinoma ( 28604730)
  • Systemic lupus erythematosus ( 21408207)
  • Systemic sclerosis ( 21779181)
  • Takayasu arteritis ( 25604533)
  • Type 1 diabetes and autoimmune thyroid diseases ( 25936594)
  • Ulcerative colitis ( 24837172 28067908)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes 14 interacting genes: DLL4 EGFL7 ELOC FBXW7 MAML1 MAML2 MAML3 NEU1 PSEN1 PSEN2 RBPJ SMAD2 SMAD3 SMAD4 18 interacting genes: CDC42SE2 CREB3 CTSA EEF1A1 ERRFI1 GLB1 IGF1 JUNB KCNA2 KCNA4 LIG4 LMNA MAF MSH5 NFYA NOTCH4 PBX2 SLC17A2
Entrez ID 4855 4758
HPRD ID 01290 09751
Ensembl ID ENSG00000204301 ENSG00000204386
Uniprot IDs A0A1U9X983 Q99466 Q5JQI0 Q99519
PDB IDs
Enriched GO Terms of Interacting Partners?
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