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CENPT

Description centromere protein T
Image No pdb structure
GO Annotations Cellular Component
  • Chromosome, Centromeric Region
  • Kinetochore
  • Condensed Chromosome Kinetochore
  • Nucleoplasm
  • Cytosol
  • Nuclear Body
Molecular Function
  • DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
  • DNA Binding
  • Protein Binding
  • Protein Heterodimerization Activity
Biological Process
  • Mitotic Cell Cycle
  • Regulation Of Transcription By RNA Polymerase II
  • Chromosome Segregation
  • CENP-A Containing Nucleosome Assembly
  • Chromosome Organization
  • Cell Division
  • Kinetochore Assembly
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Deposition of new CENPA-containing nucleosomes at the centromere
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
  • Schizophrenia ( 25056061 29483656)
Interacting Genes 9 interacting genes: APP CENPW COPS5 CYB5B DHX29 H3C1 PPCDC SNCB TCEA2
Entrez ID 80152
HPRD ID 07811
Ensembl ID ENSG00000102901
Uniprot IDs B3KPB2 Q96BT3
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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