TARBP2 and RBM14

Number of citations of the paper that reports this interaction (PubMedID 11443112)
52

Data Source:
HPRD (in vitro)

		TARBP2	RBM14
Description		TARBP2 subunit of RISC loading complex	RNA binding motif protein 14
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol RISC Complex Nuclear Body Perinuclear Region Of Cytoplasm RISC-loading Complex	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	Double-stranded RNA Binding Protein Binding Enzyme Binding SiRNA Binding MiRNA Binding Pre-mRNA Binding Identical Protein Binding Protein Homodimerization Activity Protein N-terminus Binding Pre-miRNA Binding	RNA Binding MRNA Binding Protein Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Negative Regulation Of Protein Kinase Activity Spermatid Development Single Fertilization MiRNA Metabolic Process Production Of SiRNA Involved In RNA Interference Targeting Of MRNA For Destruction Involved In RNA Interference Pre-miRNA Processing SiRNA Loading Onto RISC Involved In RNA Interference Production Of MiRNAs Involved In Gene Silencing By MiRNA Multicellular Organism Growth MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Skeletal Muscle Tissue Regeneration Positive Regulation Of Viral Genome Replication Positive Regulation Of Translation Regulation Of Viral Transcription Negative Regulation Of Defense Response To Virus By Host Positive Regulation Of Muscle Cell Differentiation Neural Precursor Cell Proliferation Regulation Of Production Of SiRNA Involved In RNA Interference Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA	Activation Of Innate Immune Response Response To Hormone Histone Deacetylation Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Centriole Replication SMAD Protein Signal Transduction Centriole Assembly
Pathways		MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis	RUNX2 regulates bone development
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Bipolar disorder ( 21926972)
Interacting Genes		22 interacting genes: AGO2 APP DICER1 EIF2AK2 HDHD2 HSPB1 IKBKG KCNIP3 MAPK8IP2 MED21 NEDD4L NEUROG1 NF2 NUDT18 PRKRA RBM14 TCEANC TGIF2 TOP1 TRAF4 VAV2 ZNF346	35 interacting genes: AKAP9 CASK CEP55 CRLF3 CTBP1 DDX17 DDX6 DMRTB1 DYNLT1 EP300 FMR1 FXR2 HNRNPK KIFAP3 KLC4 NCOA6 NDEL1 NR3C1 PARD6G PARP1 PCBP1 PRKCI QKI RBM10 RBM5 RPA2 RUNX1 RUNX2 SLAIN1 SS18 SYT1 TARBP2 UBE2I XRCC5 YWHAE
Entrez ID		6895	10432
HPRD ID		05446	11485
Ensembl ID		ENSG00000139546	ENSG00000239306
Uniprot IDs		A0A024RB49 Q15633	A0A0S2Z4Z0 A0A0S2Z567 A0A0S2Z5V2 Q96PK6
PDB IDs		2CPN 3ADL 3LLH 4WYQ 5N8L 5N8M 5ZAK 5ZAL 5ZAM	2DNP
Enriched GO Terms of Interacting Partners?
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