DST and DISC1

  • Number of citations of the paper that reports this interaction (PubMedID 17043677)
  • 168
  • Data Source:
  • BioGRID (two hybrid)

DST

DISC1

Description dystonin DISC1 scaffold protein
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer disease and age of onset ( 26830138)
  • Attention function in attention deficit hyperactive disorder ( 26174813)
  • Cerebrospinal fluid clusterin levels ( 26545630)
  • Daytime sleep phenotypes ( 27126917)
  • Heel bone mineral density ( 30598549)
  • Menarche (age at onset) ( 25231870)
  • Small cell lung carcinoma ( 28604730)
  • Alzheimer's disease ( 19118814)
  • Amyotrophic lateral sclerosis ( 19451621)
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Arterial stiffness index ( 31235810)
  • Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451)
  • Metabolite levels ( 23823483)
  • Neuranatomic and neurocognitive phenotypes ( 21483430)
  • Pelvic organ prolapse (moderate/severe) ( 26545240)
  • Response to antidepressants (symptom improvement) ( 29160301)
  • Response to antineoplastic agents ( 21659360)
  • Response to statin therapy ( 20339536)
  • Waist circumference ( 28552196)
Interacting Genes 27 interacting genes: APC CALM1 CDC5L CELSR3 CEP63 COL17A1 DCTN1 DISC1 DTNBP1 ECPAS ERBIN EXOC1 ITGB4 ITSN2 KIAA1549 KRT14 KRT5 MAPK6 MTNR1B NFYC PAK2 PRKAB2 PRKD2 SH3BP5 SMAD9 TNIK TRAF3IP1 107 interacting genes: ACTG1 ACTN2 AGTPBP1 AKAP6 ARIH2 ATF4 ATF5 ATF7IP BICD1 CCDC136 CCDC141 CCDC24 CCDC88A CDC5L CDK5RAP3 CEP126 CEP57L1 CEP63 CIT CLU COL4A1 DCTN1 DCTN2 DMD DNAJC7 DPYSL2 DPYSL3 DST DYNC1H1 EEF2 EIF3H EXOC1 EXOC4 EXOC7 FBXO41 FBXW7 FEZ1 FRYL GNB1 GNPTAB GPRASP2 GSK3B HERC2P2 IFT20 IMMT ITSN1 KALRN KANSL1 KCNQ5 KIF3A KIF3C KIFAP3 MACF1 MAP1A MEMO1 MLLT10 MPPED1 MVP MYH7 MYT1L NDE1 NDEL1 NEFM NUP160 OLFM1 PCNT PCNX4 PDE4B PGK1 PPM1E PPP4R1 PPP5C RABGAP1 RAD21 RANBP9 RASSF7 RBSN ROGDI RTRAF SH3BP5 SMARCE1 SMC2 SMC3 SNX6 SPARCL1 SPTBN4 SRGAP2 SRGAP3 STX18 SYBU SYNE1 TFIP11 TIAM2 TNKS TRAF3IP1 TRIO TSPOAP1 TUBB TUBB2A UTRN XPNPEP1 YWHAE YWHAG YWHAQ YWHAZ ZNF197 ZNF365
Entrez ID 667 27185
HPRD ID 00222 05553
Ensembl ID ENSG00000151914 ENSG00000162946
Uniprot IDs B4DGY0 B4DSS9 E9PHM6 F6QMI7 F8W9J4 Q03001 Q6P0N6 C4P094 C4P096 C4P098 C4P0A4 C4P0A5 C4P0C4 C4P0C8 C4P0D0 C4P0D1 C4P0D2 C4P0D3 Q9NRI5
PDB IDs 3GJO 5V4B
Enriched GO Terms of Interacting Partners?
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