MTMR9 and VAC14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MTMR9	VAC14
Description		myotubularin related protein 9	VAC14 component of PIKFYVE complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Cytosol Ruffle Membrane Protein-containing Complex Perinuclear Region Of Cytoplasm	Golgi Membrane Extrinsic Component Of Vacuolar Membrane Vacuolar Membrane Endoplasmic Reticulum Cytosol Endosome Membrane Early Endosome Membrane Late Endosome Membrane Intracellular Membrane-bounded Organelle PAS Complex
	Molecular Function	Protein Binding Protein Phosphatase Binding Enzyme Regulator Activity	Protein Binding Signaling Receptor Activity
	Biological Process	Phosphatidylinositol Biosynthetic Process Endocytosis Negative Regulation Of Autophagy Positive Regulation Of Phosphatase Activity Protein Stabilization Regulation Of Phosphatidylinositol Dephosphorylation	Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Positive Regulation Of Kinase Activity
Pathways		Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the late endosome membrane Synthesis of IP2, IP, and Ins in the cytosol	Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the late endosome membrane
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Bone ultrasound measurement (broadband ultrasound attenuation) ( 28472463) Extraversion ( 27918536) General factor of neuroticism ( 30867560) Retinal vascular caliber ( 21060863) Systemic lupus erythematosus ( 26316170)	Diffuse cutaneous systemic sclerosis ( 29293537) Docetaxel-induced peripheral neuropathy in metastatic castrate-resistant prostate cancer ( 27143689) High density lipoprotein cholesterol levels ( 28548082) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Pulse pressure ( 28135244)
Interacting Genes		16 interacting genes: AATK EMILIN1 ERBB3 ERBB4 EWSR1 KDM1A LNX1 MOS MTMR6 MTMR7 MTMR8 NMI PTK7 ROR2 SPG21 VAC14	53 interacting genes: ACSS1 APP ASB13 BCL2L1 BHLHE40 C11orf54 C4orf33 CASP1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 CRK DDAH2 FNDC3B GALT GINS3 HNRNPLL JMJD7 KRTAP19-5 KRTAP19-7 KYAT1 LINC00518 LPAL2 MGAT5B MPPED2 MTMR9 MVP NGB NOS1 NTAQ1 PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PRADC1 PRR13 PRR20A RBFOX2 RHOXF2 SIGLEC5 SMUG1 SNF8 SPRYD7 SRPK2 TCEANC TP53BP1 ZCWPW1 ZNF34
Entrez ID		66036	55697
HPRD ID		09377	07660
Ensembl ID		ENSG00000104643	ENSG00000103043
Uniprot IDs		Q96QG7	Q08AM6
PDB IDs
Enriched GO Terms of Interacting Partners?
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